C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: MLX, MAX dimerization protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000108788 MLX 9606 + 17:42567068-42573239 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000246912 MLX-001 42567072-42573239 protein_coding
  ENST00000346833 MLX-003 42567072-42573239 protein_coding
  ENST00000435881 MLX-002 42567068-42573239 protein_coding
  ENST00000585403 MLX-005 42567103-42571729 retained_intron
  ENST00000586393 MLX-012 42567117-42569499 retained_intron
  ENST00000588320 MLX-007 42568077-42572705 retained_intron
  ENST00000590050 MLX-004 42567072-42573239 retained_intron
  ENST00000590084 MLX-009 42567099-42569290 retained_intron
  ENST00000591024 MLX-008 42567074-42570178 protein_coding
  ENST00000591195 MLX-011 42567281-42568898 retained_intron
  ENST00000592717 MLX-010 42567102-42568104 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENST00000346833ENST00000435881ENST00000585403ENST00000588320ENST00000591024
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000346833 N/A N/A 0.781±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000435881 6.234±0.00 1.165±0.00 1.202±0.00 1.394±0.00 1.045±0.00 1.963±0.00 2.699±0.00 1.777±0.00 2.605±0.00 3.951±0.00 2.809±1.55 4.308±1.42
ENST00000585403 N/A 0.807±0.00 N/A 3.015±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000588320 2.869±0.00 N/A 4.431±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000591024 9.599±0.00 N/A 2.341±0.00 5.197±0.00 6.398±0.00 2.948±0.00 3.963±0.00 2.143±0.00 4.831±0.00 6.004±0.00 9.067±0.00 7.646±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004GR CIL_0004GR_0001 CGP 17:42561467-42573239
CIL_00045X CIL_00045X_0001 CGP 17:42567068-42577831

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000977 IDA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001227 IDA RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003677 IDA DNA binding
GO:0003700 NAS sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006112 TAS energy reserve metabolic process
GO:0006351 IEA transcription, DNA-templated
GO:0006355 NAS regulation of transcription, DNA-templated
GO:0006913 IEA nucleocytoplasmic transport
GO:0008134 IPI transcription factor binding
GO:0031325 TAS positive regulation of cellular metabolic process
GO:0042803 IPI protein homodimerization activity
GO:0044281 TAS small molecule metabolic process
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0046982 IPI protein heterodimerization activity
GO:0046983 IEA protein dimerization activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037891 mlx MAX-like protein X protein_coding Danio_rerio
ENSMUSG00000017801 Mlx MAX-like protein X protein_coding Mus_musculus

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