C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: MLX, MAX dimerization protein
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000435881 MLX-002 ENSG00000108788 9606 + 17:42567068-42573239 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENST00000435881
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000435881 6.234±0.00 1.165±0.00 1.202±0.00 1.394±0.00 1.045±0.00 1.963±0.00 2.699±0.00 1.777±0.00 2.605±0.00 3.951±0.00 2.809±1.55 4.308±1.42

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004GR CIL_0004GR_0001 CGP 17:42561467-42573239
CIL_00045X CIL_00045X_0001 CGP 17:42567068-42577831

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000977 IDA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001227 IDA RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003677 IDA DNA binding
GO:0003700 NAS sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006112 TAS energy reserve metabolic process
GO:0006351 IEA transcription, DNA-templated
GO:0006355 NAS regulation of transcription, DNA-templated
GO:0008134 IPI transcription factor binding
GO:0031325 TAS positive regulation of cellular metabolic process
GO:0042803 IPI protein homodimerization activity
GO:0044281 TAS small molecule metabolic process
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0046982 IPI protein heterodimerization activity
GO:0046983 IEA protein dimerization activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000107302 Mlx-002 protein_coding Mus_musculus 0 1212
ENSMUST00000017945 Mlx-001 protein_coding Mus_musculus 0 1112
ENSMUST00000107303 Mlx-003 protein_coding Mus_musculus 0 905
ENSMUST00000149411 Mlx-004 processed_transcript Mus_musculus 0 889
ENSMUST00000145187 Mlx-005 processed_transcript Mus_musculus 0 699
ENSMUST00000143344 Mlx-007 processed_transcript Mus_musculus 0 473
ENSMUST00000149597 Mlx-006 protein_coding Mus_musculus 0 193
ENSMUST00000134520 Psmc3ip-003 retained_intron Mus_musculus 2e-29 135
ENSMUST00000142545 Psmc3ip-004 nonsense_mediated_decay Mus_musculus 7e-18 97
ENSMUST00000126386 Psmc3ip-002 retained_intron Mus_musculus 0.00000000000002 86
ENSMUST00000019447 Psmc3ip-001 protein_coding Mus_musculus 0.00000000000002 86

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