C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ubiquitin-conjugating enzyme E2D 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000109332 UBE2D3 9606 - 4:102794383-102868896 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000321805 UBE2D3-013 102797235-102827553 protein_coding
  ENST00000338145 UBE2D3-006 102797252-102868875 protein_coding
  ENST00000343106 UBE2D3-002 102796134-102827122 protein_coding
  ENST00000349311 UBE2D3-012 102797264-102827849 protein_coding
  ENST00000350435 UBE2D3-014 102797247-102825860 protein_coding
  ENST00000357194 UBE2D3-003 102797357-102868896 protein_coding
  ENST00000394801 UBE2D3-004 102795976-102827948 protein_coding
  ENST00000394803 UBE2D3-005 102795976-102828159 protein_coding
  ENST00000394804 UBE2D3-201 102794386-102827948 protein_coding
  ENST00000453744 UBE2D3-001 102794383-102827812 protein_coding
  ENST00000502404 UBE2D3-017 102797399-102825780 protein_coding
  ENST00000502563 UBE2D3-027 102801457-102826867 nonsense_mediated_decay
  ENST00000502690 UBE2D3-011 102801523-102828029 protein_coding
  ENST00000503282 UBE2D3-025 102809430-102827520 retained_intron
  ENST00000503418 UBE2D3-021 102802561-102827835 nonsense_mediated_decay
  ENST00000503742 UBE2D3-007 102797151-102827566 retained_intron
  ENST00000504211 UBE2D3-019 102797322-102825542 protein_coding
  ENST00000505009 UBE2D3-031 102797355-102802694 retained_intron
  ENST00000505207 UBE2D3-015 102797367-102825780 protein_coding
  ENST00000505307 UBE2D3-022 102799407-102827551 nonsense_mediated_decay
  ENST00000507845 UBE2D3-016 102797385-102825785 protein_coding
  ENST00000508238 UBE2D3-009 102801469-102868861 protein_coding
  ENST00000508249 UBE2D3-010 102802612-102828064 protein_coding
  ENST00000508474 UBE2D3-008 102796134-102812973 retained_intron
  ENST00000508476 UBE2D3-018 102801454-102825559 protein_coding
  ENST00000508635 UBE2D3-024 102797403-102825540 nonsense_mediated_decay
  ENST00000508818 UBE2D3-029 102802370-102828010 retained_intron
  ENST00000508974 UBE2D3-026 102801509-102827500 nonsense_mediated_decay
  ENST00000510129 UBE2D3-028 102799467-102827522 nonsense_mediated_decay
  ENST00000510599 UBE2D3-030 102802349-102809953 retained_intron
  ENST00000513098 UBE2D3-023 102809080-102827010 processed_transcript
  ENST00000514755 UBE2D3-020 102801473-102828031 nonsense_mediated_decay
  ENST00000618836 UBE2D3-202 102794390-102810396 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000321805ENST00000343106ENST00000394801ENST00000394803ENST00000453744ENST00000505307ENST00000508474ENST00000510129ENST00000618836
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000321805 N/A N/A N/A N/A N/A N/A 30.003±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000343106 25.162±0.00 14.651±0.00 19.934±0.00 N/A 20.336±2.43 21.826±4.34 12.743±3.63 14.027±2.68 18.579±0.00 22.915±1.29 25.877±9.39 17.220±0.00 N/A N/A
ENST00000394801 28.260±0.00 10.120±0.00 N/A 9.986±0.00 N/A N/A N/A 9.362±0.00 13.573±0.93 27.644±0.00 N/A 27.274±5.53 29.142±3.42 18.717±3.46
ENST00000394803 31.461±0.00 27.947±0.00 N/A 24.743±7.65 38.024±0.00 32.768±21.81 21.467±0.00 27.437±14.32 18.236±0.00 45.745±0.00 23.893±0.00 19.752±8.97 16.295±3.49 31.609±10.66
ENST00000453744 11.142±0.00 7.197±0.00 5.571±0.00 17.576±0.00 8.166±0.00 10.343±1.79 5.646±2.10 6.595±0.95 5.470±2.45 13.436±0.39 10.671±4.30 9.724±2.32 7.752±0.00 9.272±1.80
ENST00000505307 N/A N/A N/A N/A N/A N/A N/A N/A N/A 48.473±0.00 N/A N/A N/A N/A
ENST00000508474 N/A N/A N/A N/A 6.411±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000510129 N/A N/A 47.986±0.00 55.861±0.00 69.207±0.00 65.626±0.00 46.456±0.00 77.290±0.00 70.369±0.00 N/A 51.774±0.00 62.168±0.00 N/A N/A
ENST00000618836 N/A N/A N/A 10.105±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 TAS negative regulation of transcription from RNA polymerase II promoter
GO:0000209 IDA protein polyubiquitination
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005654 TAS nucleoplasm
GO:0005768 IEA endosome
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0006281 IEA DNA repair
GO:0006351 TAS transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006464 TAS cellular protein modification process
GO:0006511 TAS ubiquitin-dependent protein catabolic process
GO:0006513 IDA protein monoubiquitination
GO:0006915 IEA apoptotic process
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0008152 IEA metabolic process
GO:0010467 TAS gene expression
GO:0016567 IDA protein ubiquitination
GO:0016881 IEA acid-amino acid ligase activity
GO:0030509 TAS BMP signaling pathway
GO:0032480 TAS negative regulation of type I interferon production
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0043161 IDA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045087 TAS innate immune response
GO:0061418 TAS regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0070062 IDA extracellular vesicular exosome
GO:0070936 IDA protein K48-linked ubiquitination
GO:0070979 IDA protein K11-linked ubiquitination
GO:0071456 TAS cellular response to hypoxia

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000028252 ube2d2l ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast), like protein_coding Danio_rerio
ENSMUSG00000078578 Ube2d3 ubiquitin-conjugating enzyme E2D 3 protein_coding Mus_musculus

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