C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: purinergic receptor P2X, ligand-gated ion channel, 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000109991 P2RX3 9606 + 11:57338374-57370600 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263314 P2RX3-001 57338517-57370600 protein_coding
  ENST00000533436 P2RX3-002 57338374-57340727 processed_transcript
  ENST00000534820 P2RX3-003 57347424-57350701 nonsense_mediated_decay
  ENST00000616487 P2RX3-201 57338475-57370076 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000263314ENST00000533436ENST00000534820ENST00000616487
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000263314 N/A 0.044±0.00 N/A N/A 0.021±0.00 0.391±0.00 0.300±0.00 0.165±0.00 N/A N/A 0.092±0.08 0.047±0.02 0.807±0.06
ENST00000533436 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.847±0.00
ENST00000534820 0.029±0.00 0.122±0.00 0.075±0.00 0.203±0.00 0.090±0.00 N/A 0.197±0.00 N/A 0.120±0.00 N/A 0.041±0.00 N/A N/A
ENST00000616487 0.061±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.231±0.00 0.040±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002LO CIL_0002LO_0002 CGP 11:57325985-57370600

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001614 IEA:NAS purinergic nucleotide receptor activity
GO:0001666 IEA response to hypoxia
GO:0004931 NAS extracellular ATP-gated cation channel activity
GO:0005216 IEA ion channel activity
GO:0005524 NAS:IEA ATP binding
GO:0005639 IBA integral component of nuclear inner membrane
GO:0005791 IEA rough endoplasmic reticulum
GO:0005794 IEA Golgi apparatus
GO:0005887 TAS integral component of plasma membrane
GO:0006810 TAS transport
GO:0006811 IEA ion transport
GO:0006812 IEA cation transport
GO:0007165 TAS signal transduction
GO:0007268 IEA synaptic transmission
GO:0007274 IEA neuromuscular synaptic transmission
GO:0009266 IEA response to temperature stimulus
GO:0009408 IEA response to heat
GO:0009409 IEA response to cold
GO:0009612 IEA response to mechanical stimulus
GO:0009743 IEA response to carbohydrate
GO:0010033 IEA response to organic substance
GO:0010524 NAS positive regulation of calcium ion transport into cytosol
GO:0014832 IEA urinary bladder smooth muscle contraction
GO:0016020 IEA membrane
GO:0019228 IEA neuronal action potential
GO:0030424 IEA axon
GO:0030432 IEA peristalsis
GO:0033198 IEA response to ATP
GO:0035590 IEA purinergic nucleotide receptor signaling pathway
GO:0043005 IEA neuron projection
GO:0043025 IEA neuronal cell body
GO:0043195 IEA terminal bouton
GO:0043197 IEA dendritic spine
GO:0043235 IDA receptor complex
GO:0045121 IEA membrane raft
GO:0048167 IEA regulation of synaptic plasticity
GO:0048266 IEA behavioral response to pain
GO:0050850 NAS positive regulation of calcium-mediated signaling
GO:0050909 IEA sensory perception of taste
GO:0051260 IEA protein homooligomerization
GO:0098655 NAS cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010477 p2rx3a purinergic receptor P2X, ligand-gated ion channel, 3a protein_coding Danio_rerio
ENSDARG00000029718 p2rx3b purinergic receptor P2X, ligand-gated ion channel, 3b protein_coding Danio_rerio
ENSMUSG00000027071 P2rx3 purinergic receptor P2X, ligand-gated ion channel, 3 protein_coding Mus_musculus

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