C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: purinergic receptor P2X, ligand-gated ion channel, 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027071 P2rx3 10090 - 2:84998583-85037462 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028465 P2rx3-002 84998583-85035487 protein_coding
  ENSMUST00000111613 P2rx3-001 84998642-85037462 protein_coding
  ENSMUST00000111616 P2rx3-003 84998843-85035322 protein_coding
  ENSMUST00000127839 P2rx3-005 85032054-85033194 processed_transcript
  ENSMUST00000145285 P2rx3-004 85024917-85033310 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; TestisENSMUST00000028465
Transcript ID Testis
ENSMUST00000028465 36.292±6.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002NZ CIL_0002NZ_0002 CGP 2:84998583-85047109

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001614 IBA purinergic nucleotide receptor activity
GO:0001666 IMP response to hypoxia
GO:0004931 IGI extracellular ATP-gated cation channel activity
GO:0005524 IEA ATP binding
GO:0005639 IBA integral component of nuclear inner membrane
GO:0005791 IEA rough endoplasmic reticulum
GO:0005794 IEA Golgi apparatus
GO:0005887 ISS integral component of plasma membrane
GO:0006811 IMP ion transport
GO:0006812 IMP cation transport
GO:0007268 IMP synaptic transmission
GO:0007274 IMP neuromuscular synaptic transmission
GO:0009266 IMP response to temperature stimulus
GO:0009408 IMP response to heat
GO:0009409 IMP response to cold
GO:0009612 IMP response to mechanical stimulus
GO:0009743 IMP response to carbohydrate
GO:0010033 IMP response to organic substance
GO:0014832 IMP urinary bladder smooth muscle contraction
GO:0019228 IEA neuronal action potential
GO:0030424 IDA axon
GO:0030432 IMP peristalsis
GO:0033198 IMP response to ATP
GO:0035590 IEA purinergic nucleotide receptor signaling pathway
GO:0043005 IDA neuron projection
GO:0043025 IEA neuronal cell body
GO:0043195 IEA terminal bouton
GO:0043197 IEA dendritic spine
GO:0043235 ISO receptor complex
GO:0045121 IEA membrane raft
GO:0048167 IMP regulation of synaptic plasticity
GO:0048266 IMP behavioral response to pain
GO:0050909 IGI sensory perception of taste
GO:0051260 IEA protein homooligomerization
GO:0098655 IGI cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010477 p2rx3a purinergic receptor P2X, ligand-gated ion channel, 3a protein_coding Danio_rerio
ENSDARG00000029718 p2rx3b purinergic receptor P2X, ligand-gated ion channel, 3b protein_coding Danio_rerio
ENSG00000109991 P2RX3 purinergic receptor P2X, ligand-gated ion channel, 3 protein_coding Homo_sapiens

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