C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: calcium/calmodulin-dependent protein kinase kinase 2, beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000110931 CAMKK2 9606 - 12:121237691-121298308 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000324774 CAMKK2-001 121237697-121298308 protein_coding
  ENST00000337174 CAMKK2-005 121237697-121298057 protein_coding
  ENST00000347034 CAMKK2-006 121237697-121298057 protein_coding
  ENST00000392473 CAMKK2-002 121243588-121298308 protein_coding
  ENST00000392474 CAMKK2-011 121237691-121274531 protein_coding
  ENST00000402834 CAMKK2-010 121240547-121296710 protein_coding
  ENST00000404169 CAMKK2-008 121240525-121296753 protein_coding
  ENST00000412367 CAMKK2-009 121240525-121296686 protein_coding
  ENST00000446440 CAMKK2-003 121243588-121298057 protein_coding
  ENST00000535524 CAMKK2-015 121253261-121296687 processed_transcript
  ENST00000538733 CAMKK2-004 121237697-121298057 protein_coding
  ENST00000539380 CAMKK2-016 121268636-121274370 processed_transcript
  ENST00000542540 CAMKK2-017 121263900-121274370 retained_intron
  ENST00000543477 CAMKK2-013 121274152-121297563 protein_coding
  ENST00000544485 CAMKK2-014 121274265-121297336 protein_coding
  ENST00000545538 CAMKK2-012 121237770-121260542 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000392474ENST00000402834ENST00000412367ENST00000545538
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000392474 4.733±0.00 N/A 8.298±5.03 4.152±0.00 3.187±0.00 1.334±1.25 2.978±0.00 4.428±0.00 3.200±0.00 0.457±0.00 4.823±0.56 4.353±0.36 4.456±0.00
ENST00000402834 N/A 1.027±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000412367 N/A N/A N/A N/A N/A N/A 1.268±0.00 N/A N/A N/A N/A N/A 1.426±0.00
ENST00000545538 2.703±0.00 N/A 6.180±0.00 1.000±0.00 2.604±0.00 N/A N/A 1.211±0.00 0.989±0.36 0.762±0.68 7.119±3.39 2.976±0.00 1.424±0.64

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002ZK CIL_0002ZK_0001 CGP 12:121209857-121298308
CIL_0002ZJ CIL_0002ZJ_0001 CGP 12:121237691-121399896

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000165 TAS MAPK cascade
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004683 IEA calmodulin-dependent protein kinase activity
GO:0004713 TAS:IEA protein tyrosine kinase activity
GO:0005509 IDA calcium ion binding
GO:0005515 IEA protein binding
GO:0005516 TAS calmodulin binding
GO:0005524 IEA ATP binding
GO:0005622 TAS intracellular
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0006468 IDA:IEA protein phosphorylation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 TAS peptidyl-tyrosine phosphorylation
GO:0019722 TAS calcium-mediated signaling
GO:0042995 IEA cell projection
GO:0045859 TAS regulation of protein kinase activity
GO:0045893 TAS positive regulation of transcription, DNA-templated
GO:0046777 IDA protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078645 CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta protein_coding Danio_rerio
ENSMUSG00000029471 Camkk2 calcium/calmodulin-dependent protein kinase kinase 2, beta protein_coding Mus_musculus

Loading