C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: actin related protein 2/3 complex, subunit 3, 21kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000111229 ARPC3 9606 - 12:110434825-110450422 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000228825 ARPC3-001 110434825-110450407 protein_coding
  ENST00000426440 ARPC3-007 110436178-110450311 protein_coding
  ENST00000467622 ARPC3-006 110434910-110437299 retained_intron
  ENST00000471641 ARPC3-005 110442644-110450285 processed_transcript
  ENST00000475777 ARPC3-002 110444883-110450422 retained_intron
  ENST00000476566 ARPC3-004 110436587-110440507 retained_intron
  ENST00000547365 ARPC3-011 110436658-110445587 protein_coding
  ENST00000548878 ARPC3-008 110436735-110450268 retained_intron
  ENST00000549408 ARPC3-012 110445069-110445485 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000228825
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000228825 82.417±0.00 181.898±0.00 17.302±0.00 58.044±10.34 58.597±18.12 51.338±8.19 22.534±15.22 56.337±29.09 42.530±22.95 76.411±43.67 21.278±10.84 93.402±46.60 162.504±21.74 65.139±12.07

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005200 IDA structural constituent of cytoskeleton
GO:0005515 IPI protein binding
GO:0005829 TAS cytosol
GO:0005856 IEA cytoskeleton
GO:0005885 IEA:IDA Arp2/3 protein complex
GO:0005925 IDA focal adhesion
GO:0006928 TAS cellular component movement
GO:0015629 TAS actin cytoskeleton
GO:0016020 IDA membrane
GO:0030027 IEA lamellipodium
GO:0030833 IEA regulation of actin filament polymerization
GO:0034314 IEA:IDA Arp2/3 complex-mediated actin nucleation
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0045087 TAS innate immune response
GO:0051015 IDA actin filament binding
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057882 arpc3 actin related protein 2/3 complex, subunit 3 protein_coding Danio_rerio
ENSMUSG00000029465 Arpc3 actin related protein 2/3 complex, subunit 3 protein_coding Mus_musculus

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