C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: myosin, light chain 2, regulatory, cardiac, slow
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000111245 MYL2 9606 - 12:110910819-110920722 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000228841 MYL2-001 110910819-110920577 protein_coding
  ENST00000546404 MYL2-004 110918829-110920722 retained_intron
  ENST00000548438 MYL2-006 110910918-110920575 protein_coding
  ENST00000549029 MYL2-007 110913133-110914290 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000228841ENST00000548438ENST00000549029
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000228841 0.185±0.00 0.243±0.00 0.410±0.00 0.186±0.00 95.904±91.27 0.730±0.20 4158.750±3535.14 0.207±0.00 3.365±3.08 0.191±0.04 1388.078±439.43 0.829±0.32 84.406±0.00 68.994±68.89
ENST00000548438 N/A N/A N/A 0.052±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.044±0.00 N/A
ENST00000549029 0.301±0.00 N/A N/A 0.148±0.00 N/A 0.496±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008YU CIL_0008YU_0001 VISTA 12:110628804-111231731
CIL_000903 CIL_000903_0001 VISTA 12:110757593-111358448

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003007 IEA heart morphogenesis
GO:0003785 IDA actin monomer binding
GO:0005509 IDA:IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005829 TAS cytosol
GO:0005856 IDA cytoskeleton
GO:0006942 TAS regulation of striated muscle contraction
GO:0007507 IEA heart development
GO:0008307 NAS structural constituent of muscle
GO:0009791 IEA post-embryonic development
GO:0015629 IDA actin cytoskeleton
GO:0016459 TAS myosin complex
GO:0030016 NAS myofibril
GO:0030017 TAS sarcomere
GO:0030049 TAS muscle filament sliding
GO:0030308 IMP negative regulation of cell growth
GO:0032036 NAS myosin heavy chain binding
GO:0042694 IEA muscle cell fate specification
GO:0048747 IEA muscle fiber development
GO:0055003 ISS cardiac myofibril assembly
GO:0055010 IMP ventricular cardiac muscle tissue morphogenesis
GO:0060047 ISS heart contraction
GO:0060048 IEA cardiac muscle contraction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043349 MYL2 (1 of 2) myosin, light chain 2, regulatory, cardiac, slow protein_coding Danio_rerio
ENSDARG00000053424 myl2b myosin, light polypeptide 2b, regulatory, cardiac, slow protein_coding Danio_rerio
ENSMUSG00000013936 Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow protein_coding Mus_musculus

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