C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: myosin, light polypeptide 2, regulatory, cardiac, slow
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000013936 Myl2 10090 + 5:122100951-122113472 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000014080 Myl2-001 122100951-122106854 protein_coding
  ENSMUST00000111750 Myl2-007 122100957-122105293 protein_coding
  ENSMUST00000111751 Myl2-012 122100983-122113472 protein_coding
  ENSMUST00000123913 Myl2-010 122103179-122106848 processed_transcript
  ENSMUST00000126006 Myl2-008 122103913-122105003 protein_coding
  ENSMUST00000139213 Myl2-002 122100980-122104905 protein_coding
  ENSMUST00000146733 Myl2-009 122101797-122104706 processed_transcript
  ENSMUST00000147178 Myl2-004 122101161-122102753 protein_coding
  ENSMUST00000150535 Myl2-005 122101385-122104888 protein_coding
  ENSMUST00000152744 Myl2-011 122103181-122106854 processed_transcript
  ENSMUST00000153816 Myl2-006 122101580-122103928 protein_coding
  ENSMUST00000155612 Myl2-003 122101032-122105036 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000014080ENSMUST00000111750ENSMUST00000111751ENSMUST00000123913ENSMUST00000152744ENSMUST00000155612
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000014080 N/A N/A 0.020±0.00 3.006±0.54 N/A 4053.257±249.99 3.393±2.86 0.378±0.29 N/A 499.455±284.90 N/A N/A
ENSMUST00000111750 N/A N/A 0.018±0.00 0.940±0.32 N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000111751 N/A N/A N/A N/A N/A N/A N/A N/A 0.065±0.00 N/A N/A 0.006±0.00
ENSMUST00000123913 N/A 0.051±0.00 0.160±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000152744 0.168±0.06 N/A 0.177±0.09 0.329±0.00 0.226±0.00 N/A N/A 0.091±0.00 0.197±0.07 N/A 0.191±0.00 N/A
ENSMUST00000155612 N/A N/A 0.075±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008TJ CIL_0008TJ_0002 VISTA 5:121625608-122227679
CIL_000903 CIL_000903_0002 VISTA 5:121732502-122333355
CIL_0008YU CIL_0008YU_0002 VISTA 5:121792218-122394768
CIL_0001G2 CIL_0001G2_0002 CGP 5:121858387-122113472

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003007 IGI heart morphogenesis
GO:0003785 IEA actin monomer binding
GO:0005509 ISO calcium ion binding
GO:0005515 IEA protein binding
GO:0005856 IEA cytoskeleton
GO:0007507 IMP heart development
GO:0009791 IGI post-embryonic development
GO:0015629 IEA actin cytoskeleton
GO:0016459 IEA myosin complex
GO:0030016 IDA myofibril
GO:0030308 IEA negative regulation of cell growth
GO:0042694 IMP muscle cell fate specification
GO:0048747 IGI muscle fiber development
GO:0055003 IMP cardiac myofibril assembly
GO:0055010 IEA ventricular cardiac muscle tissue morphogenesis
GO:0060047 IDA heart contraction
GO:0060048 IGI cardiac muscle contraction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043349 MYL2 (1 of 2) myosin, light chain 2, regulatory, cardiac, slow protein_coding Danio_rerio
ENSDARG00000053424 myl2b myosin, light polypeptide 2b, regulatory, cardiac, slow protein_coding Danio_rerio
ENSG00000111245 MYL2 myosin, light chain 2, regulatory, cardiac, slow protein_coding Homo_sapiens

Loading