C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dual specificity phosphatase 16
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000111266 DUSP16 9606 - 12:12474210-12562383 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000228862 DUSP16-201 12475897-12562383 protein_coding
  ENST00000298573 DUSP16-001 12474210-12562383 protein_coding
  ENST00000536236 DUSP16-004 12521327-12560886 processed_transcript
  ENST00000539940 DUSP16-003 12521024-12561125 protein_coding
  ENST00000541207 DUSP16-002 12521081-12561077 protein_coding
  ENST00000545864 DUSP16-005 12477886-12506187 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000228862ENST00000298573
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000228862 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.208±0.00 N/A N/A N/A
ENST00000298573 5.318±0.00 0.735±0.00 4.010±3.31 3.161±0.00 2.497±1.45 0.941±0.68 2.906±0.46 3.690±2.66 9.585±0.00 5.028±0.00 8.194±0.93 3.905±0.51 1.076±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003I2 CIL_0003I2_0001 CGP 12:12357079-12562383
CIL_0000K8 CIL_0000K8_0001 CGP 12:12474210-12645108

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000188 IEA inactivation of MAPK activity
GO:0004721 TAS phosphoprotein phosphatase activity
GO:0004725 IEA protein tyrosine phosphatase activity
GO:0005515 IEA protein binding
GO:0005634 IBA nucleus
GO:0005737 IBA cytoplasm
GO:0005829 IEA cytosol
GO:0006470 IEA protein dephosphorylation
GO:0008138 IBA:IEA protein tyrosine/serine/threonine phosphatase activity
GO:0016311 TAS:IEA dephosphorylation
GO:0016791 IEA phosphatase activity
GO:0017017 IEA MAP kinase tyrosine/serine/threonine phosphatase activity
GO:0031410 IEA cytoplasmic vesicle
GO:0035335 IEA peptidyl-tyrosine dephosphorylation
GO:0043409 IEA negative regulation of MAPK cascade
GO:0045204 TAS MAPK export from nucleus
GO:0045209 TAS MAPK phosphatase export from nucleus, leptomycin B sensitive

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077617 dusp16 dual specificity phosphatase 16 protein_coding Danio_rerio
ENSMUSG00000030203 Dusp16 dual specificity phosphatase 16 protein_coding Mus_musculus

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