C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lymphotoxin beta receptor (TNFR superfamily, member 3)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000111321 LTBR 9606 + 12:6375045-6391571 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000228918 LTBR-001 6384033-6391563 protein_coding
  ENST00000440421 LTBR-011 6385459-6386371 retained_intron
  ENST00000441074 LTBR-009 6388926-6391571 retained_intron
  ENST00000444814 LTBR-002 6385840-6387576 retained_intron
  ENST00000535739 LTBR-013 6384176-6386443 retained_intron
  ENST00000536876 LTBR-014 6384170-6386445 protein_coding
  ENST00000539925 LTBR-003 6375429-6391224 protein_coding
  ENST00000541005 LTBR-008 6388254-6390735 retained_intron
  ENST00000541102 LTBR-010 6385119-6391111 protein_coding
  ENST00000542830 LTBR-005 6375224-6385277 processed_transcript
  ENST00000543190 LTBR-012 6384253-6388506 protein_coding
  ENST00000543542 LTBR-007 6388392-6389052 retained_intron
  ENST00000544454 LTBR-006 6385111-6388825 nonsense_mediated_decay
  ENST00000545445 LTBR-015 6384998-6385455 retained_intron
  ENST00000546296 LTBR-004 6375045-6385157 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000228918ENST00000440421ENST00000441074ENST00000536876ENST00000539925ENST00000541102ENST00000543190ENST00000544454
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000228918 14.543±0.00 26.262±0.00 1.976±1.74 52.071±0.00 35.859±0.00 6.736±6.05 27.387±20.84 42.624±33.57 50.540±0.00 28.249±0.00 55.690±39.03 51.836±10.83 14.724±7.55
ENST00000440421 N/A N/A 0.236±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000441074 N/A N/A 0.871±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.809±0.00
ENST00000536876 N/A N/A 0.554±0.00 N/A N/A N/A 4.824±0.00 N/A N/A N/A N/A N/A N/A
ENST00000539925 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.768±0.00 N/A N/A N/A
ENST00000541102 20.504±0.00 20.069±0.00 0.272±0.00 N/A 21.804±9.68 N/A 5.172±0.00 N/A N/A N/A 123.664±0.00 22.363±0.00 12.779±1.98
ENST00000543190 N/A N/A N/A N/A N/A 0.624±0.00 N/A N/A N/A 4.919±0.00 N/A N/A N/A
ENST00000544454 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.667±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI:IEA protein binding
GO:0006915 IEA apoptotic process
GO:0007165 TAS signal transduction
GO:0016021 IEA integral component of membrane
GO:0016032 IEA viral process
GO:0031625 IPI ubiquitin protein ligase binding
GO:0042802 IPI identical protein binding
GO:0043011 IEA myeloid dendritic cell differentiation
GO:0043123 IEP positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0046330 IMP positive regulation of JNK cascade
GO:0071260 IEP cellular response to mechanical stimulus
GO:2001238 IMP positive regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000088018 CABZ01053483.1 Uncharacterized protein protein_coding Danio_rerio
ENSMUSG00000030339 Ltbr lymphotoxin B receptor protein_coding Mus_musculus

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