C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: C2 calcium-dependent domain containing 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000111731 C2CD5 9606 - 12:22448583-22544546 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000333957 C2CD5-001 22448583-22544546 protein_coding
  ENST00000396028 C2CD5-006 22449545-22544409 protein_coding
  ENST00000446597 C2CD5-003 22449545-22544409 protein_coding
  ENST00000535304 C2CD5-008 22534707-22544189 retained_intron
  ENST00000535555 C2CD5-010 22484795-22513324 protein_coding
  ENST00000536386 C2CD5-005 22449545-22544409 protein_coding
  ENST00000537643 C2CD5-019 22470897-22477338 processed_transcript
  ENST00000539615 C2CD5-016 22449815-22472305 protein_coding
  ENST00000540245 C2CD5-013 22470836-22472445 retained_intron
  ENST00000540703 C2CD5-015 22518096-22525697 processed_transcript
  ENST00000541310 C2CD5-004 22478028-22544546 retained_intron
  ENST00000542676 C2CD5-002 22449581-22544253 protein_coding
  ENST00000542683 C2CD5-018 22484755-22524480 nonsense_mediated_decay
  ENST00000542768 C2CD5-012 22484338-22490182 retained_intron
  ENST00000543797 C2CD5-011 22482562-22506967 retained_intron
  ENST00000543855 C2CD5-009 22484743-22506819 processed_transcript
  ENST00000543888 C2CD5-014 22456971-22458864 retained_intron
  ENST00000545552 C2CD5-007 22449656-22544492 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000333957ENST00000396028ENST00000446597ENST00000540703ENST00000542676ENST00000542683ENST00000545552
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000333957 1.532±0.00 1.684±0.00 2.162±0.00 6.629±0.00 3.596±2.06 2.920±0.29 0.602±0.36 3.761±0.00 0.449±0.00 1.044±0.14 N/A 2.508±0.33 2.070±0.88 2.467±0.78
ENST00000396028 N/A N/A N/A N/A N/A 1.577±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000446597 N/A N/A N/A N/A N/A 1.272±0.00 N/A N/A 3.990±0.00 1.302±0.00 0.139±0.00 N/A N/A N/A
ENST00000540703 N/A N/A 9.304±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000542676 N/A N/A 2.315±0.00 N/A N/A N/A 0.619±0.00 0.753±0.00 N/A N/A N/A 2.306±0.21 N/A N/A
ENST00000542683 N/A N/A 5.078±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000545552 N/A N/A N/A 2.773±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005PQ CIL_0005PQ_0001 CGP 12:22063773-22544546
CIL_0004XA CIL_0004XA_0001 CGP 12:22448583-22690665

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005509 IDA calcium ion binding
GO:0005515 IEA protein binding
GO:0005544 IDA calcium-dependent phospholipid binding
GO:0005886 IDA plasma membrane
GO:0005938 IDA cell cortex
GO:0006906 IEA vesicle fusion
GO:0010828 ISS positive regulation of glucose transport
GO:0030659 IDA cytoplasmic vesicle membrane
GO:0031340 IMP positive regulation of vesicle fusion
GO:0032587 IDA ruffle membrane
GO:0032869 IDA cellular response to insulin stimulus
GO:0038028 ISS insulin receptor signaling pathway via phosphatidylinositol 3-kinase
GO:0065002 IMP intracellular protein transmembrane transport
GO:0072659 IEA protein localization to plasma membrane
GO:0090314 IMP positive regulation of protein targeting to membrane
GO:2001275 IEA positive regulation of glucose import in response to insulin stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076350 C2CD5 (1 of 2) C2 calcium-dependent domain containing 5 protein_coding Danio_rerio
ENSDARG00000094590 C2CD5 (2 of 2) C2 calcium-dependent domain containing 5 protein_coding Danio_rerio
ENSMUSG00000030279 C2cd5 C2 calcium-dependent domain containing 5 protein_coding Mus_musculus

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