C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein phosphatase 2, regulatory subunit B', delta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000112640 PPP2R5D 9606 + 6:42984499-43012342 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000230402 PPP2R5D-006 42984600-43012340 nonsense_mediated_decay
  ENST00000394110 PPP2R5D-004 42984553-43012342 protein_coding
  ENST00000461010 PPP2R5D-007 42984652-43011327 protein_coding
  ENST00000467447 PPP2R5D-009 43007012-43008219 retained_intron
  ENST00000470467 PPP2R5D-008 43006600-43012340 protein_coding
  ENST00000472118 PPP2R5D-003 42984554-43012340 protein_coding
  ENST00000482315 PPP2R5D-010 43008279-43010500 retained_intron
  ENST00000485511 PPP2R5D-001 42984499-43012342 protein_coding
  ENST00000486843 PPP2R5D-011 43009113-43010894 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000230402ENST00000394110ENST00000461010ENST00000470467ENST00000472118ENST00000485511
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000230402 N/A N/A N/A N/A N/A 1.887±0.00 N/A N/A N/A N/A 1.083±0.00 N/A N/A N/A
ENST00000394110 N/A N/A 0.474±0.00 N/A N/A N/A N/A 2.060±0.00 N/A 0.459±0.00 N/A N/A N/A N/A
ENST00000461010 5.276±0.00 N/A 2.448±0.00 7.315±0.00 N/A N/A 1.572±0.00 2.738±0.00 2.565±0.00 2.887±0.00 5.897±0.00 8.205±1.94 N/A N/A
ENST00000470467 2.684±0.00 3.977±0.00 N/A 9.981±0.00 N/A 8.252±0.00 N/A 7.528±0.00 2.971±0.00 5.510±0.00 6.886±0.00 10.517±2.83 10.219±5.87 19.579±0.00
ENST00000472118 3.244±0.00 3.262±0.00 N/A 5.356±0.00 10.774±0.00 N/A 5.120±0.00 N/A N/A 6.644±0.00 12.652±0.00 N/A N/A N/A
ENST00000485511 3.915±0.00 N/A N/A 3.818±1.39 0.965±0.00 6.520±0.00 3.810±2.37 5.834±0.00 2.837±0.56 N/A 7.039±0.00 9.119±4.84 11.041±2.37 12.441±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000159 IEA protein phosphatase type 2A complex
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002755 TAS MyD88-dependent toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0004722 TAS protein serine/threonine phosphatase activity
GO:0005488 IEA binding
GO:0005515 IPI protein binding
GO:0005634 TAS nucleus
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0005975 TAS carbohydrate metabolic process
GO:0006006 TAS glucose metabolic process
GO:0006096 TAS glycolytic process
GO:0006112 TAS energy reserve metabolic process
GO:0007165 IEA signal transduction
GO:0007399 TAS nervous system development
GO:0008601 IEA protein phosphatase type 2A regulator activity
GO:0016311 TAS dephosphorylation
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034146 TAS toll-like receptor 5 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0034166 TAS toll-like receptor 10 signaling pathway
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0044281 TAS small molecule metabolic process
GO:0045087 TAS innate immune response
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0050790 IEA regulation of catalytic activity
GO:0051403 TAS stress-activated MAPK cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014428 ppp2r5d protein phosphatase 2, regulatory subunit B', delta protein_coding Danio_rerio
ENSMUSG00000059409 Ppp2r5d protein phosphatase 2, regulatory subunit B', delta protein_coding Mus_musculus

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