C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutamate receptor, metabotropic 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000113262 GRM6 9606 - 5:178978327-178996206 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000231188 GRM6-201 178978327-178995123 protein_coding
  ENST00000517717 GRM6-001 178981657-178995298 protein_coding
  ENST00000518082 GRM6-003 178986443-178988972 retained_intron
  ENST00000519003 GRM6-004 178982807-178986252 retained_intron
  ENST00000519175 GRM6-002 178995278-178996206 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENST00000231188ENST00000517717ENST00000518082ENST00000519003
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000231188 0.095±0.00 0.206±0.00 0.083±0.03 0.114±0.01 0.038±0.00 0.063±0.02 0.230±0.00 0.049±0.02 0.053±0.00 0.025±0.00 0.048±0.02 0.014±0.00
ENST00000517717 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.043±0.03
ENST00000518082 N/A N/A N/A N/A N/A 0.078±0.00 N/A N/A N/A N/A N/A N/A
ENST00000519003 N/A N/A 0.642±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 IDA Golgi membrane
GO:0001640 IEA adenylate cyclase inhibiting G-protein coupled glutamate receptor activity
GO:0001642 IBA group III metabotropic glutamate receptor activity
GO:0004930 TAS:IEA G-protein coupled receptor activity
GO:0005515 IPI protein binding
GO:0005789 IDA endoplasmic reticulum membrane
GO:0005886 TAS plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0007165 IEA signal transduction
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007196 IBA adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
GO:0007216 IMP G-protein coupled glutamate receptor signaling pathway
GO:0007268 IEA synaptic transmission
GO:0007626 IEA locomotory behavior
GO:0008066 IMP glutamate receptor activity
GO:0009584 TAS detection of visible light
GO:0016021 IEA integral component of membrane
GO:0035841 IEA new growing cell tip
GO:0042734 IBA presynaptic membrane
GO:0042803 IPI protein homodimerization activity
GO:0042995 IEA cell projection
GO:0050908 IMP detection of light stimulus involved in visual perception
GO:0050953 IEA sensory perception of light stimulus
GO:0051966 IBA regulation of synaptic transmission, glutamatergic
GO:0060041 IEA retina development in camera-type eye
GO:0090280 IMP positive regulation of calcium ion import

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017742 grm6a glutamate receptor, metabotropic 6a protein_coding Danio_rerio
ENSDARG00000025671 grm6b glutamate receptor, metabotropic 6b protein_coding Danio_rerio
ENSMUSG00000000617 Grm6 glutamate receptor, metabotropic 6 protein_coding Mus_musculus

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