C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glucagon
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000115263 GCG 9606 - 2:162142873-162152404 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000375497 GCG-201 162143905-162152404 protein_coding
  ENST00000418842 GCG-001 162142873-162152403 protein_coding
  ENST00000483769 GCG-004 162143178-162144415 retained_intron
  ENST00000492913 GCG-002 162145359-162152237 retained_intron
  ENST00000497568 GCG-003 162144695-162147393 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastColonLiverOvaryENST00000418842ENST00000483769ENST00000492913
Transcript ID Breast Colon Liver Ovary
ENST00000418842 N/A 5.467±1.54 N/A 0.022±0.00
ENST00000483769 N/A N/A 0.262±0.00 N/A
ENST00000492913 0.532±0.00 1.592±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00039X CIL_00039X_0001 CGP 2:161992241-162152404
CIL_0003S0 CIL_0003S0_0002 CGP 2:162142873-162245151

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005102 TAS receptor binding
GO:0005179 IBA:IEA hormone activity
GO:0005515 IPI protein binding
GO:0005576 TAS:IEA extracellular region
GO:0005615 IBA extracellular space
GO:0005737 IEA cytoplasm
GO:0005788 TAS endoplasmic reticulum lumen
GO:0005886 TAS plasma membrane
GO:0006112 TAS energy reserve metabolic process
GO:0007165 TAS signal transduction
GO:0007186 TAS G-protein coupled receptor signaling pathway
GO:0007188 IBA adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007631 TAS feeding behavior
GO:0008283 TAS cell proliferation
GO:0010737 IBA protein kinase A signaling
GO:0010800 IEA positive regulation of peptidyl-threonine phosphorylation
GO:0030819 IEA positive regulation of cAMP biosynthetic process
GO:0031769 IBA glucagon receptor binding
GO:0032092 IEA positive regulation of protein binding
GO:0033138 IEA positive regulation of peptidyl-serine phosphorylation
GO:0034774 TAS secretory granule lumen
GO:0035774 IBA positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0035948 IEA positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter
GO:0042594 IBA response to starvation
GO:0042802 IPI identical protein binding
GO:0043066 IBA negative regulation of apoptotic process
GO:0044267 TAS cellular protein metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045860 IEA positive regulation of protein kinase activity
GO:0050796 TAS regulation of insulin secretion
GO:0051571 IEA positive regulation of histone H3-K4 methylation
GO:0070374 IEA positive regulation of ERK1 and ERK2 cascade
GO:0071377 TAS cellular response to glucagon stimulus
GO:0090280 IEA positive regulation of calcium ion import
GO:1900118 IEA negative regulation of execution phase of apoptosis
GO:2001243 IEA negative regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040907 gcgb glucagon b protein_coding Danio_rerio
ENSDARG00000079296 gcga glucagon a protein_coding Danio_rerio
ENSMUSG00000000394 Gcg glucagon protein_coding Mus_musculus

Loading