C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glucagon
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000000394 Gcg 10090 - 2:62474530-62483650 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000102733 Gcg-001 62474530-62483650 protein_coding
  ENSMUST00000136686 Gcg-002 62475733-62483645 protein_coding
  ENSMUST00000155624 Gcg-003 62476571-62480678 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonLiverLungOvaryPlacentaTestisENSMUST00000102733ENSMUST00000136686ENSMUST00000155624
Transcript ID Adrenal Bladder Brain Breast Colon Liver Lung Ovary Placenta Testis
ENSMUST00000102733 N/A 0.014±0.00 0.475±0.09 0.077±0.00 21.287±3.46 0.040±0.02 0.063±0.00 0.185±0.06 0.042±0.00 N/A
ENSMUST00000136686 N/A N/A N/A 0.224±0.14 10.572±0.00 0.049±0.00 N/A N/A 0.036±0.00 0.065±0.00
ENSMUST00000155624 0.178±0.00 N/A N/A 0.230±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00039X CIL_00039X_0002 CGP 2:62330073-62483650
CIL_0003S0 CIL_0003S0_0003 CGP 2:62474530-62574075

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005179 IBA hormone activity
GO:0005515 IEA protein binding
GO:0005615 IDA extracellular space
GO:0005737 IDA cytoplasm
GO:0007188 IBA adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0010737 IMP protein kinase A signaling
GO:0010800 IDA positive regulation of peptidyl-threonine phosphorylation
GO:0030819 IDA positive regulation of cAMP biosynthetic process
GO:0031769 IBA glucagon receptor binding
GO:0032092 IDA positive regulation of protein binding
GO:0033138 IDA positive regulation of peptidyl-serine phosphorylation
GO:0034774 TAS secretory granule lumen
GO:0035774 IDA positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0035948 IDA positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter
GO:0042594 IBA response to starvation
GO:0042802 IEA identical protein binding
GO:0043066 IDA negative regulation of apoptotic process
GO:0045860 IDA positive regulation of protein kinase activity
GO:0050796 IDA regulation of insulin secretion
GO:0051571 IGI positive regulation of histone H3-K4 methylation
GO:0070374 IDA positive regulation of ERK1 and ERK2 cascade
GO:0090280 IDA positive regulation of calcium ion import
GO:1900118 IDA negative regulation of execution phase of apoptosis
GO:2001243 IDA negative regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040907 gcgb glucagon b protein_coding Danio_rerio
ENSDARG00000079296 gcga glucagon a protein_coding Danio_rerio
ENSG00000115263 GCG glucagon protein_coding Homo_sapiens

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