C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: docking protein 1, 62kDa (downstream of tyrosine kinase 1)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000115325 DOK1 9606 + 2:74549026-74557554 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000233668 DOK1-001 74554086-74557554 protein_coding
  ENST00000340004 DOK1-002 74554731-74557551 protein_coding
  ENST00000409429 DOK1-006 74549026-74557536 protein_coding
  ENST00000429631 DOK1-012 74555206-74556621 nonsense_mediated_decay
  ENST00000464613 DOK1-005 74555132-74557513 retained_intron
  ENST00000474924 DOK1-009 74554738-74555636 retained_intron
  ENST00000475191 DOK1-010 74554750-74555926 retained_intron
  ENST00000480318 DOK1-004 74554738-74557114 processed_transcript
  ENST00000482206 DOK1-008 74554738-74555597 retained_intron
  ENST00000485132 DOK1-011 74549071-74555387 processed_transcript
  ENST00000488613 DOK1-007 74554160-74555231 processed_transcript
  ENST00000489958 DOK1-003 74554734-74557185 processed_transcript
  ENST00000496966 DOK1-013 74554742-74556776 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastENST00000340004ENST00000409429
Transcript ID Breast
ENST00000340004 20.201±0.00
ENST00000409429 19.599±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002DM CIL_0002DM_0002 CGP 2:74549026-74648338

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005057 IEA receptor signaling protein activity
GO:0005158 IEA insulin receptor binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0007165 TAS signal transduction
GO:0007166 TAS cell surface receptor signaling pathway
GO:0007169 TAS transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007265 IEA Ras protein signal transduction
GO:0008286 TAS insulin receptor signaling pathway
GO:0035556 IEA intracellular signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000051935 dok1b docking protein 1b protein_coding Danio_rerio
ENSDARG00000078108 dok1a docking protein 1a protein_coding Danio_rerio
ENSMUSG00000068335 Dok1 docking protein 1 protein_coding Mus_musculus

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