C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: docking protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000068335 Dok1 10090 - 6:83030934-83033471 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000089651 Dok1-001 83030934-83033471 protein_coding
  ENSMUST00000149918 Dok1-002 83030940-83033468 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000089651ENSMUST00000149918
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000089651 2.908±1.10 3.441±0.63 6.839±1.47 0.742±0.09 2.971±2.70 3.019±1.35 0.703±0.08 1.179±0.26 5.170±4.90 4.534±0.51 0.905±0.20 4.718±3.30 1.815±0.44 0.291±0.20
ENSMUST00000149918 1.657±0.07 1.909±0.61 2.003±0.00 0.131±0.00 2.126±0.44 N/A N/A 0.270±0.04 1.190±0.98 1.428±0.39 0.147±0.04 1.704±0.73 0.355±0.05 0.108±0.05

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000165 TAS MAPK cascade
GO:0005057 IPI receptor signaling protein activity
GO:0005158 IEA insulin receptor binding
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005737 IEA cytoplasm
GO:0007169 IPI transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007265 IPI Ras protein signal transduction
GO:0035556 IPI intracellular signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000051935 dok1b docking protein 1b protein_coding Danio_rerio
ENSDARG00000078108 dok1a docking protein 1a protein_coding Danio_rerio
ENSG00000115325 DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1) protein_coding Homo_sapiens

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