C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: insulin-like growth factor binding protein 2, 36kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000115457 IGFBP2 9606 + 2:216632828-216664436 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000233809 IGFBP2-001 216633395-216664436 protein_coding
  ENST00000434997 IGFBP2-003 216632828-216661917 protein_coding
  ENST00000436812 IGFBP2-005 216660733-216664409 protein_coding
  ENST00000456764 IGFBP2-004 216659618-216664285 protein_coding
  ENST00000490362 IGFBP2-002 216633429-216664433 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000233809ENST00000436812ENST00000456764ENST00000490362
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000233809 55.137±0.00 22.596±0.00 2.179±0.00 10.575±10.15 24.714±18.89 54.323±51.14 17.949±14.81 88.301±38.46 189.917±186.24 43.268±41.14 6.563±0.00 121.662±99.99 153.347±35.10 89.214±26.15
ENST00000436812 N/A N/A 2.122±0.00 1.186±0.00 N/A 4.783±0.00 N/A 15.841±0.00 5.526±0.00 N/A 0.901±0.00 24.303±12.22 N/A N/A
ENST00000456764 N/A N/A N/A N/A N/A N/A N/A N/A 2.296±0.00 N/A N/A 66.505±0.00 49.571±3.40 N/A
ENST00000490362 N/A N/A N/A 0.111±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005MF CIL_0005MF_0001 CGP 2:216498189-216664436
CIL_0000AM CIL_0000AM_0002 CGP 2:216632828-216695525

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001558 IEA regulation of cell growth
GO:0005515 IPI protein binding
GO:0005520 IEA insulin-like growth factor binding
GO:0005576 ISS:IEA extracellular region
GO:0005615 IDA extracellular space
GO:0007165 IEA signal transduction
GO:0007565 IEA female pregnancy
GO:0007568 IEA aging
GO:0007584 IEA response to nutrient
GO:0009612 IEA response to mechanical stimulus
GO:0010226 IEA response to lithium ion
GO:0016324 IEA apical plasma membrane
GO:0031410 IEA cytoplasmic vesicle
GO:0031994 IDA insulin-like growth factor I binding
GO:0031995 ISS insulin-like growth factor II binding
GO:0032355 IEA response to estradiol
GO:0032526 IEA response to retinoic acid
GO:0032870 IEA cellular response to hormone stimulus
GO:0042104 IDA positive regulation of activated T cell proliferation
GO:0042493 IEA response to drug
GO:0043567 ISS regulation of insulin-like growth factor receptor signaling pathway
GO:0043627 IEA response to estrogen
GO:0044267 TAS cellular protein metabolic process
GO:0048545 IEA response to steroid hormone
GO:0051384 IEA response to glucocorticoid
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031422 igfbp2b insulin-like growth factor binding protein 2b protein_coding Danio_rerio
ENSDARG00000052470 igfbp2a insulin-like growth factor binding protein 2a protein_coding Danio_rerio
ENSMUSG00000039323 Igfbp2 insulin-like growth factor binding protein 2 protein_coding Mus_musculus

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