C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interleukin 1 receptor-like 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000115602 IL1RL1 9606 + 2:102311502-102352037 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000233954 IL1RL1-001 102311502-102352037 protein_coding
  ENST00000311734 IL1RL1-002 102337148-102346100 protein_coding
  ENST00000404917 IL1RL1-201 102311502-102346099 protein_coding
  ENST00000409584 IL1RL1-008 102337258-102344951 protein_coding
  ENST00000427077 IL1RL1-003 102337288-102343756 nonsense_mediated_decay
  ENST00000447231 IL1RL1-004 102311568-102338891 protein_coding
  ENST00000463990 IL1RL1-006 102337250-102339466 retained_intron
  ENST00000473175 IL1RL1-007 102311529-102340196 processed_transcript
  ENST00000482701 IL1RL1-005 102337281-102343109 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000233954ENST00000311734ENST00000404917ENST00000409584ENST00000427077
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000233954 N/A N/A N/A N/A N/A N/A N/A N/A 2.324±0.00 N/A N/A N/A N/A N/A
ENST00000311734 10.120±0.00 N/A 0.868±0.00 5.315±0.00 N/A 2.586±0.00 N/A 19.238±0.00 N/A N/A N/A 0.153±0.00 37.937±21.30 N/A
ENST00000404917 N/A 0.436±0.00 1.433±0.00 N/A N/A N/A 0.219±0.15 16.720±0.00 3.739±0.00 16.729±8.08 N/A 0.295±0.01 15.866±3.31 0.217±0.00
ENST00000409584 15.704±0.00 N/A N/A 4.486±4.40 1.968±0.00 7.710±0.00 0.317±0.22 55.429±0.00 3.198±0.00 36.524±19.92 N/A 0.558±0.24 85.000±85.30 0.309±0.00
ENST00000427077 N/A N/A N/A N/A N/A N/A N/A N/A N/A 36.449±0.00 0.142±0.00 0.850±0.00 51.354±24.54 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004R1 CIL_0004R1_0001 CGP 2:102186973-102352037
CIL_0004R0 CIL_0004R0_0001 CGP 2:102311502-102398775

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002113 IEA interleukin-33 binding
GO:0002114 IEA interleukin-33 receptor activity
GO:0002826 IEA negative regulation of T-helper 1 type immune response
GO:0004896 TAS cytokine receptor activity
GO:0004908 IEA interleukin-1 receptor activity
GO:0005057 TAS receptor signaling protein activity
GO:0005515 IPI:IEA protein binding
GO:0005576 IEA extracellular region
GO:0006955 NAS immune response
GO:0007165 TAS:IEA signal transduction
GO:0009897 IEA external side of plasma membrane
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0031012 IEA extracellular matrix
GO:0032689 IEA negative regulation of interferon-gamma production
GO:0032754 IEA positive regulation of interleukin-5 production
GO:0035556 TAS intracellular signal transduction
GO:0038172 IEA interleukin-33-mediated signaling pathway
GO:0043032 IEA positive regulation of macrophage activation
GO:0043124 IEA negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0050729 IEA positive regulation of inflammatory response
GO:0090197 IEA positive regulation of chemokine secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000090844 IL1R1 interleukin 1 receptor, type I protein_coding Danio_rerio
ENSMUSG00000026069 Il1rl1 interleukin 1 receptor-like 1 protein_coding Mus_musculus

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