C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interleukin 1 receptor-like 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026069 Il1rl1 10090 + 1:40429570-40465415 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000053043 Il1rl1-201 40440628-40465396 protein_coding
  ENSMUST00000097772 Il1rl1-001 40439627-40465415 protein_coding
  ENSMUST00000173514 Il1rl1-002 40439776-40448148 protein_coding
  ENSMUST00000173881 Il1rl1-004 40436589-40441407 protein_coding
  ENSMUST00000174335 Il1rl1-003 40429570-40446723 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000053043ENSMUST00000097772ENSMUST00000173514ENSMUST00000173881ENSMUST00000174335
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000053043 N/A 0.130±0.05 0.364±0.00 0.023±0.00 0.945±0.26 0.144±0.00 0.188±0.00 0.065±0.03 1.456±0.93 N/A 0.078±0.02 0.262±0.09 0.018±0.01 0.023±0.01
ENSMUST00000097772 N/A N/A N/A N/A 0.240±0.00 0.138±0.06 0.159±0.00 N/A 0.457±0.04 N/A N/A 0.339±0.00 N/A N/A
ENSMUST00000173514 0.188±0.00 0.085±0.04 N/A N/A 0.434±0.08 0.870±0.40 0.056±0.00 0.023±0.01 0.669±0.04 N/A N/A 0.109±0.03 0.036±0.02 0.015±0.00
ENSMUST00000173881 N/A 0.524±0.23 N/A N/A N/A N/A N/A 0.460±0.17 0.204±0.00 N/A 0.217±0.00 0.860±0.20 N/A N/A
ENSMUST00000174335 0.714±0.00 N/A N/A 0.076±0.00 N/A 0.644±0.00 N/A 0.112±0.00 N/A 0.807±0.00 N/A 0.387±0.15 N/A 0.031±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004R1 CIL_0004R1_0002 CGP 1:40324627-40465415
CIL_0004R0 CIL_0004R0_0002 CGP 1:40429570-40500854

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002113 IPI interleukin-33 binding
GO:0002114 IPI interleukin-33 receptor activity
GO:0002826 IGI negative regulation of T-helper 1 type immune response
GO:0004908 IEA interleukin-1 receptor activity
GO:0005576 IEA extracellular region
GO:0009897 IDA external side of plasma membrane
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0031012 IDA extracellular matrix
GO:0032689 IGI negative regulation of interferon-gamma production
GO:0032754 IGI positive regulation of interleukin-5 production
GO:0038172 IPI interleukin-33-mediated signaling pathway
GO:0043032 IMP positive regulation of macrophage activation
GO:0043124 IDA negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0050729 IMP positive regulation of inflammatory response
GO:0090197 IMP positive regulation of chemokine secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000090844 IL1R1 interleukin 1 receptor, type I protein_coding Danio_rerio
ENSG00000115602 IL1RL1 interleukin 1 receptor-like 1 protein_coding Homo_sapiens

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