C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ERBB receptor feedback inhibitor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000116285 ERRFI1 9606 - 1:8004404-8026308 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000377482 ERRFI1-001 8011719-8026308 protein_coding
  ENST00000467067 ERRFI1-002 8013427-8015633 protein_coding
  ENST00000469499 ERRFI1-004 8013739-8026296 protein_coding
  ENST00000474874 ERRFI1-003 8004404-8026283 protein_coding
  ENST00000487559 ERRFI1-005 8014040-8026296 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000377482ENST00000467067ENST00000469499
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000377482 47.643±0.00 8.496±0.00 4.200±0.00 7.059±4.66 5.277±3.56 5.303±0.00 3.824±3.09 46.926±12.96 34.377±27.77 16.804±0.00 22.713±0.00 18.495±8.73 38.563±5.84 12.408±0.00
ENST00000467067 N/A N/A N/A 1.184±0.00 N/A N/A N/A 31.489±0.00 N/A N/A N/A N/A N/A N/A
ENST00000469499 N/A N/A N/A N/A N/A 1.822±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007VW CIL_0007VW_0001 VISTA 1:7770379-8371827

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005100 TAS Rho GTPase activator activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 ISS cytoplasm
GO:0006950 TAS response to stress
GO:0007175 ISS negative regulation of epidermal growth factor-activated receptor activity
GO:0019900 IEA kinase binding
GO:0019901 IPI protein kinase binding
GO:0031234 ISS extrinsic component of cytoplasmic side of plasma membrane
GO:0031953 IDA negative regulation of protein autophosphorylation
GO:0032321 TAS positive regulation of Rho GTPase activity
GO:0042059 IEA negative regulation of epidermal growth factor receptor signaling pathway
GO:0043589 ISS skin morphogenesis
GO:0045616 ISS regulation of keratinocyte differentiation
GO:0048286 ISS lung alveolus development
GO:0060426 ISS lung vasculature development
GO:0060428 ISS lung epithelium development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070171 errfi1 ERBB receptor feedback inhibitor 1 protein_coding Danio_rerio
ENSDARG00000086098 ERRFI1 (2 of 2) ERBB receptor feedback inhibitor 1 protein_coding Danio_rerio
ENSMUSG00000028967 Errfi1 ERBB receptor feedback inhibitor 1 protein_coding Mus_musculus

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