Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Accession	Transcript Name	Contained in Gene	Tax ID	Strand	Position	Biotype
Transcript Info
Description:	ERBB receptor feedback inhibitor 1
ENST00000377482	ERRFI1-001	ENSG00000116285	9606	-	1:8011719-8026308	protein_coding

Expression Patterns

Transcript ID	Adipose	Adrenal	Bladder	Brain	Breast	Colon	Heart	Kidney	Liver	Lung	Muscle	Ovary	Placenta	Testis
ENST00000377482	47.643±0.00	8.496±0.00	4.200±0.00	7.059±4.66	5.277±3.56	5.303±0.00	3.824±3.09	46.926±12.96	34.377±27.77	16.804±0.00	22.713±0.00	18.495±8.73	38.563±5.84	12.408±0.00

Conserved Regions
Region ID	Sub-Region	Region Type	Position
CIL_0007VW	CIL_0007VW_0001	VISTA	1:7770379-8371827

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0005100	TAS	Rho GTPase activator activity
GO:0005515	IPI	protein binding
GO:0005634	IEA	nucleus
GO:0005737	ISS	cytoplasm
GO:0006950	TAS	response to stress
GO:0007175	ISS	negative regulation of epidermal growth factor-activated receptor activity
GO:0019900	IEA	kinase binding
GO:0019901	IPI	protein kinase binding
GO:0031234	ISS	extrinsic component of cytoplasmic side of plasma membrane
GO:0031953	IDA	negative regulation of protein autophosphorylation
GO:0032321	TAS	positive regulation of Rho GTPase activity
GO:0042059	IEA	negative regulation of epidermal growth factor receptor signaling pathway
GO:0043589	ISS	skin morphogenesis
GO:0045616	ISS	regulation of keratinocyte differentiation
GO:0048286	ISS	lung alveolus development
GO:0060426	ISS	lung vasculature development
GO:0060428	ISS	lung epithelium development

Homologs
ENSEMBL Accession	Gene Name	Biotype	Species	E-Value	Bit Score
ENSMUST00000030811	Errfi1-001	protein_coding	Mus_musculus	0	1733
ENSMUST00000073600	Errfi1-002	protein_coding	Mus_musculus	0	1611
ENSMUST00000128640	Errfi1-003	processed_transcript	Mus_musculus	5e-30	137

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