C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RAP1A, member of RAS oncogene family
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000116473 RAP1A 9606 + 1:111542218-111716691 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000356415 RAP1A-002 111542218-111713113 protein_coding
  ENST00000369709 RAP1A-001 111619783-111716691 protein_coding
  ENST00000433097 RAP1A-003 111619777-111704405 protein_coding
  ENST00000494982 RAP1A-004 111627469-111712696 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000356415ENST00000369709ENST00000433097ENST00000494982
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000356415 23.098±0.00 33.059±0.00 1.778±0.00 8.641±5.34 13.207±5.82 11.671±0.00 7.581±4.69 6.135±0.41 14.971±0.91 25.765±15.67 7.159±6.65 8.953±3.89 8.516±1.68 13.686±11.97
ENST00000369709 5.033±0.00 4.974±0.00 0.831±0.00 4.218±1.36 3.459±0.00 8.993±5.71 2.411±1.88 2.669±0.43 6.217±5.31 5.175±0.00 2.578±1.83 2.424±1.23 2.573±0.08 2.868±1.65
ENST00000433097 24.013±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 12.345±0.00 17.266±0.00 6.960±0.00
ENST00000494982 23.070±0.00 12.524±0.00 N/A 16.679±0.00 8.839±0.00 N/A N/A N/A N/A N/A N/A 10.959±0.00 23.728±0.00 11.575±2.49

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000186 TAS activation of MAPKK activity
GO:0003924 IEA GTPase activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005622 IEA intracellular
GO:0005737 IDA cytoplasm
GO:0005769 ISS early endosome
GO:0005770 ISS late endosome
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0006112 TAS energy reserve metabolic process
GO:0006184 IEA GTP catabolic process
GO:0006886 IEA intracellular protein transport
GO:0006913 IEA nucleocytoplasmic transport
GO:0007165 TAS:IEA signal transduction
GO:0007264 IEA small GTPase mediated signal transduction
GO:0007596 TAS blood coagulation
GO:0008565 IDA protein transporter activity
GO:0010976 ISS positive regulation of neuron projection development
GO:0015031 IDA:IEA protein transport
GO:0016020 IEA membrane
GO:0017016 IEA Ras GTPase binding
GO:0017034 ISS Rap guanyl-nucleotide exchange factor activity
GO:0030054 ISS cell junction
GO:0030168 TAS platelet activation
GO:0032045 IEA guanyl-nucleotide exchange factor complex
GO:0032403 IDA protein complex binding
GO:0032486 IMP Rap protein signal transduction
GO:0032854 ISS positive regulation of Rap GTPase activity
GO:0038180 ISS nerve growth factor signaling pathway
GO:0043005 IEA neuron projection
GO:0044281 TAS small molecule metabolic process
GO:0045860 ISS positive regulation of protein kinase activity
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048471 IDA perinuclear region of cytoplasm
GO:0050796 TAS regulation of insulin secretion
GO:0061028 IMP establishment of endothelial barrier
GO:0070062 IDA extracellular vesicular exosome
GO:0070374 ISS positive regulation of ERK1 and ERK2 cascade
GO:0071320 IDA cellular response to cAMP
GO:1901888 IMP regulation of cell junction assembly
GO:1990090 ISS cellular response to nerve growth factor stimulus
GO:2000301 IEA negative regulation of synaptic vesicle exocytosis
GO:2001214 ISS positive regulation of vasculogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000068798 Rap1a RAS-related protein-1a protein_coding Mus_musculus

Loading