C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: aldo-keto reductase family 1, member A1 (aldehyde reductase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000117448 AKR1A1 9606 + 1:45550543-45570049 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000351829 AKR1A1-002 45551067-45570049 protein_coding
  ENST00000372070 AKR1A1-001 45550543-45570049 protein_coding
  ENST00000434299 AKR1A1-004 45550804-45568068 protein_coding
  ENST00000471651 AKR1A1-007 45551068-45567588 protein_coding
  ENST00000473038 AKR1A1-003 45567549-45570049 processed_transcript
  ENST00000475919 AKR1A1-009 45568614-45570047 processed_transcript
  ENST00000475985 AKR1A1-010 45569050-45570045 processed_transcript
  ENST00000476957 AKR1A1-006 45550854-45568624 processed_transcript
  ENST00000481885 AKR1A1-011 45551067-45568025 protein_coding
  ENST00000487654 AKR1A1-013 45568147-45570044 processed_transcript
  ENST00000495913 AKR1A1-008 45567982-45570049 processed_transcript
  ENST00000496999 AKR1A1-005 45550846-45567213 processed_transcript
  ENST00000497973 AKR1A1-012 45566869-45570049 processed_transcript
  ENST00000621846 AKR1A1-201 45550783-45570048 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000351829ENST00000372070ENST00000434299ENST00000471651ENST00000473038ENST00000476957ENST00000481885ENST00000495913ENST00000497973ENST00000621846
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000351829 33.216±0.00 50.610±0.00 37.645±0.00 8.891±0.61 21.017±8.65 21.370±11.21 5.081±2.92 74.419±11.35 35.726±28.56 22.115±7.87 8.456±5.39 24.968±9.84 45.380±6.15 24.092±11.93
ENST00000372070 N/A N/A N/A 1.118±0.00 N/A 3.204±0.00 0.366±0.00 N/A N/A N/A N/A 1.985±0.00 N/A N/A
ENST00000434299 N/A N/A N/A N/A N/A N/A 5.735±0.00 N/A N/A N/A 10.309±0.00 20.537±0.00 N/A 7.766±0.00
ENST00000471651 N/A N/A N/A N/A 3.289±0.00 N/A N/A N/A N/A N/A N/A 2.502±0.00 N/A N/A
ENST00000473038 N/A N/A N/A N/A 3.124±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000476957 N/A N/A N/A N/A 18.081±0.00 N/A N/A N/A N/A N/A N/A 18.161±0.00 20.334±0.00 N/A
ENST00000481885 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 32.593±0.00 N/A
ENST00000495913 N/A N/A N/A 8.997±0.00 N/A N/A N/A N/A N/A N/A N/A 54.941±0.00 N/A N/A
ENST00000497973 N/A N/A N/A N/A N/A N/A N/A N/A N/A 19.278±0.00 N/A N/A N/A N/A
ENST00000621846 N/A N/A N/A 6.667±0.00 N/A N/A 2.449±0.00 N/A N/A N/A 3.597±0.40 21.446±5.76 18.648±2.67 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004032 TAS alditol:NADP+ 1-oxidoreductase activity
GO:0005615 IDA extracellular space
GO:0005829 IEA cytosol
GO:0006006 TAS glucose metabolic process
GO:0006081 TAS cellular aldehyde metabolic process
GO:0009055 TAS electron carrier activity
GO:0016324 IEA apical plasma membrane
GO:0016491 IEA oxidoreductase activity
GO:0019853 IEA L-ascorbic acid biosynthetic process
GO:0042840 IEA D-glucuronate catabolic process
GO:0046185 IEA aldehyde catabolic process
GO:0047939 IEA L-glucuronate reductase activity
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052030 akr1a1b aldo-keto reductase family 1, member A1b (aldehyde reductase) protein_coding Danio_rerio
ENSMUSG00000028692 Akr1a1 aldo-keto reductase family 1, member A1 (aldehyde reductase) protein_coding Mus_musculus

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