C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: aldo-keto reductase family 1, member A1 (aldehyde reductase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028692 Akr1a1 10090 - 4:116636510-116651680 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030455 Akr1a1-001 116636510-116651680 protein_coding
  ENSMUST00000126146 Akr1a1-004 116636511-116638014 processed_transcript
  ENSMUST00000128010 Akr1a1-002 116636511-116651396 processed_transcript
  ENSMUST00000128059 Akr1a1-003 116639102-116649474 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030455ENSMUST00000126146ENSMUST00000128059
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030455 359.388±10.62 539.164±38.66 255.262±26.62 206.565±78.59 305.045±77.30 366.481±13.39 122.882±3.65 1504.735±91.80 250.875±47.15 364.444±4.40 98.502±3.42 288.666±77.79 220.059±92.46 48.957±18.59
ENSMUST00000126146 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 162.523±10.43 N/A
ENSMUST00000128059 N/A N/A N/A 297.816±0.00 N/A N/A N/A N/A N/A N/A N/A 580.447±0.00 356.736±101.78 70.760±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001PT CIL_0001PT_0002 CGP 4:116601052-116651680

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004032 ISS alditol:NADP+ 1-oxidoreductase activity
GO:0005615 IEA extracellular space
GO:0005829 IDA cytosol
GO:0008106 NAS alcohol dehydrogenase (NADP+) activity
GO:0016324 IDA apical plasma membrane
GO:0019853 IDA L-ascorbic acid biosynthetic process
GO:0042840 IDA D-glucuronate catabolic process
GO:0046185 IDA aldehyde catabolic process
GO:0047939 IDA L-glucuronate reductase activity
GO:0055114 IEA oxidation-reduction process
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052030 akr1a1b aldo-keto reductase family 1, member A1b (aldehyde reductase) protein_coding Danio_rerio
ENSG00000117448 AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) protein_coding Homo_sapiens

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