C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: coagulation factor III (thromboplastin, tissue factor)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000117525 F3 9606 - 1:94529225-94541800 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000334047 F3-001 94529225-94541800 protein_coding
  ENST00000370207 F3-002 94529310-94541637 protein_coding
  ENST00000478217 F3-003 94532997-94536164 processed_transcript
  ENST00000480356 F3-004 94533106-94541759 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000334047ENST00000370207ENST00000478217ENST00000480356
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000334047 45.199±0.00 6.772±0.00 0.486±0.00 12.021±0.00 11.920±8.48 8.129±3.17 6.658±1.13 4.050±3.97 0.185±0.00 20.092±10.03 1.356±0.00 14.947±7.17 34.400±6.14 22.059±8.09
ENST00000370207 N/A N/A N/A N/A N/A N/A N/A 2.097±0.00 0.540±0.00 19.064±0.00 0.354±0.00 8.980±6.25 34.289±0.00 12.573±0.00
ENST00000478217 N/A N/A 0.622±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000480356 N/A N/A 0.532±0.00 N/A 6.640±0.00 6.023±0.00 N/A 0.317±0.00 N/A 6.958±0.00 N/A 3.408±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009DI CIL_0009DI_0001 VISTA 1:93946469-94547443

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001938 IDA positive regulation of endothelial cell proliferation
GO:0002020 IPI protease binding
GO:0002541 IDA activation of plasma proteins involved in acute inflammatory response
GO:0002543 IC activation of blood coagulation via clotting cascade
GO:0005515 IPI:IEA protein binding
GO:0005543 IDA phospholipid binding
GO:0005615 IDA extracellular space
GO:0005886 TAS plasma membrane
GO:0006919 IDA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007596 TAS blood coagulation
GO:0007598 TAS blood coagulation, extrinsic pathway
GO:0009986 IDA cell surface
GO:0010641 IDA positive regulation of platelet-derived growth factor receptor signaling pathway
GO:0016021 IEA integral component of membrane
GO:0030335 TAS positive regulation of cell migration
GO:0031012 IDA extracellular matrix
GO:0031233 IC intrinsic component of external side of plasma membrane
GO:0045766 IDA positive regulation of angiogenesis
GO:0050927 IC positive regulation of positive chemotaxis
GO:0051897 IMP positive regulation of protein kinase B signaling
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005673 f3b coagulation factor IIIb protein_coding Danio_rerio
ENSDARG00000021013 f3a coagulation factor IIIa protein_coding Danio_rerio
ENSMUSG00000028128 F3 coagulation factor III protein_coding Mus_musculus

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