C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: signal peptidase complex subunit 2 homolog (S. cerevisiae)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000118363 SPCS2 9606 + 11:74949247-74979031 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263672 SPCS2-001 74949247-74979031 protein_coding
  ENST00000526361 SPCS2-003 74949264-74977348 protein_coding
  ENST00000526883 SPCS2-008 74949524-74969691 protein_coding
  ENST00000527225 SPCS2-007 74949279-74977056 processed_transcript
  ENST00000527290 SPCS2-005 74949271-74965169 retained_intron
  ENST00000528265 SPCS2-006 74949278-74977617 processed_transcript
  ENST00000530257 SPCS2-002 74949261-74977156 protein_coding
  ENST00000532972 SPCS2-004 74949265-74977087 protein_coding
  ENST00000610881 SPCS2-201 74949247-74979031 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000263672ENST00000526361ENST00000526883ENST00000527290ENST00000528265ENST00000532972
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000263672 2.197±0.00 N/A 2.699±0.00 4.783±0.74 3.015±0.83 3.867±0.00 0.986±0.00 4.581±0.00 5.558±0.00 3.494±0.00 0.520±0.00 6.627±0.59 N/A 7.047±0.00
ENST00000526361 6.975±0.00 N/A 2.809±0.00 2.934±0.00 1.580±0.00 N/A N/A N/A N/A 4.238±0.00 N/A 19.841±13.43 17.592±0.00 8.200±0.00
ENST00000526883 9.869±0.00 N/A 5.725±0.00 N/A 7.613±0.00 6.867±0.00 N/A N/A N/A N/A 1.407±0.00 36.112±21.12 28.717±0.00 14.475±0.00
ENST00000527290 N/A N/A N/A N/A N/A N/A 3.797±0.00 N/A N/A N/A N/A 35.748±0.00 50.477±0.00 15.137±0.00
ENST00000528265 23.334±0.00 17.714±0.00 N/A 34.866±0.00 29.074±0.00 29.809±0.00 8.357±0.00 35.799±0.00 17.270±0.00 9.454±0.00 9.326±0.00 44.472±11.22 16.763±0.00 35.745±26.47
ENST00000532972 N/A N/A N/A N/A 4.577±0.00 4.214±0.00 2.095±0.00 9.720±0.00 N/A 3.942±0.00 2.617±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008I3 CIL_0008I3_0001 VISTA 11:74770295-75374240

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005787 IEA signal peptidase complex
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006412 TAS translation
GO:0006465 IEA signal peptide processing
GO:0006508 IEA proteolysis
GO:0006614 TAS SRP-dependent cotranslational protein targeting to membrane
GO:0008233 IEA peptidase activity
GO:0010467 TAS gene expression
GO:0016021 IEA integral component of membrane
GO:0044267 TAS cellular protein metabolic process
GO:0050796 TAS regulation of insulin secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042823 spcs2 signal peptidase complex subunit 2 homolog (S. cerevisiae) protein_coding Danio_rerio
ENSMUSG00000035227 Spcs2 signal peptidase complex subunit 2 homolog (S. cerevisiae) protein_coding Mus_musculus

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