C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: caspase 8 associated protein 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000118412 CASP8AP2 9606 + 6:89829894-89874436 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000237177 CASP8AP2-003 89829939-89874436 processed_transcript
  ENST00000419040 CASP8AP2-001 89829900-89862793 protein_coding
  ENST00000547893 CASP8AP2-006 89829931-89857349 processed_transcript
  ENST00000548224 CASP8AP2-007 89829941-89874434 processed_transcript
  ENST00000551025 CASP8AP2-201 89829900-89871412 protein_coding
  ENST00000552401 CASP8AP2-004 89829894-89862793 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartLiverLungMuscleOvaryPlacentaENST00000237177ENST00000419040ENST00000548224ENST00000551025
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Liver Lung Muscle Ovary Placenta
ENST00000237177 0.216±0.00 1.111±0.00 0.441±0.00 N/A N/A N/A 0.188±0.01 0.830±0.00 0.737±0.00 1.373±0.00 0.561±0.09 0.619±0.00
ENST00000419040 N/A N/A N/A N/A 2.407±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000548224 N/A N/A N/A N/A 0.705±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000551025 0.264±0.00 N/A N/A 0.839±0.00 0.424±0.00 2.262±0.00 N/A N/A 0.843±0.00 N/A 0.968±0.00 0.853±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006BU CIL_0006BU_0002 CGP 6:89642499-89874436
CIL_0006BV CIL_0006BV_0002 CGP 6:89829894-89896120

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002020 IEA protease binding
GO:0003677 IEA DNA binding
GO:0005515 IEA protein binding
GO:0006919 IEA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0008625 IEA extrinsic apoptotic signaling pathway via death domain receptors
GO:0008656 IEA cysteine-type endopeptidase activator activity involved in apoptotic process
GO:0042802 IEA identical protein binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000022718 casp8ap2 CASP8 associated protein 2 protein_coding Danio_rerio
ENSMUSG00000028282 Casp8ap2 caspase 8 associated protein 2 protein_coding Mus_musculus

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