C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: caspase 8 associated protein 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028282 Casp8ap2 10090 + 4:32615451-32653265 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000029950 Casp8ap2-001 32615478-32653265 protein_coding
  ENSMUST00000108178 Casp8ap2-002 32624084-32653265 protein_coding
  ENSMUST00000124278 Casp8ap2-004 32615451-32631810 processed_transcript
  ENSMUST00000127619 Casp8ap2-003 32615470-32639501 processed_transcript
  ENSMUST00000178925 Casp8ap2-201 32615473-32653265 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000029950ENSMUST00000108178ENSMUST00000124278ENSMUST00000178925
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000029950 0.307±0.10 0.342±0.17 0.342±0.00 0.509±0.03 0.593±0.32 0.457±0.20 0.109±0.05 0.291±0.16 0.317±0.19 0.543±0.22 0.276±0.10 0.921±0.35 0.737±0.06 0.385±0.10
ENSMUST00000108178 N/A 0.309±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000124278 N/A N/A N/A N/A N/A N/A 1.550±0.00 1.696±0.00 0.580±0.08 2.926±0.00 N/A N/A N/A N/A
ENSMUST00000178925 0.521±0.23 N/A 0.948±0.25 2.443±0.48 0.429±0.29 0.357±0.03 0.201±0.01 0.247±0.10 2.180±1.48 0.515±0.27 0.447±0.17 1.780±1.11 5.237±1.71 0.434±0.26

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002020 IPI protease binding
GO:0003677 IEA DNA binding
GO:0003714 ISS transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0005739 ISS mitochondrion
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006919 IDA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007049 IEA cell cycle
GO:0008625 IDA extrinsic apoptotic signaling pathway via death domain receptors
GO:0008656 IDA cysteine-type endopeptidase activator activity involved in apoptotic process
GO:0016605 ISS PML body
GO:0032184 ISS SUMO polymer binding
GO:0036337 ISS Fas signaling pathway
GO:0042802 IDA identical protein binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000022718 casp8ap2 CASP8 associated protein 2 protein_coding Danio_rerio
ENSG00000118412 CASP8AP2 caspase 8 associated protein 2 protein_coding Homo_sapiens

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