C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serum/glucocorticoid regulated kinase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000118515 SGK1 9606 - 6:134169246-134318112 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000237305 SGK1-009 134169252-134174896 protein_coding
  ENST00000367855 SGK1-019 134169284-134174842 retained_intron
  ENST00000367857 SGK1-011 134169353-134174865 protein_coding
  ENST00000367858 SGK1-001 134169246-134318058 protein_coding
  ENST00000413996 SGK1-010 134169250-134175991 protein_coding
  ENST00000460769 SGK1-004 134214954-134262059 protein_coding
  ENST00000461976 SGK1-021 134173555-134317911 protein_coding
  ENST00000472859 SGK1-028 134173909-134174861 retained_intron
  ENST00000473704 SGK1-005 134171105-134172134 retained_intron
  ENST00000474427 SGK1-007 134169248-134174866 retained_intron
  ENST00000475719 SGK1-018 134170106-134174864 protein_coding
  ENST00000475882 SGK1-016 134172724-134174247 retained_intron
  ENST00000477460 SGK1-014 134169252-134172907 retained_intron
  ENST00000484353 SGK1-003 134180255-134262017 processed_transcript
  ENST00000485771 SGK1-008 134214945-134230481 processed_transcript
  ENST00000489458 SGK1-012 134171651-134174379 processed_transcript
  ENST00000490149 SGK1-013 134172777-134174191 retained_intron
  ENST00000524387 SGK1-022 134173064-134230467 processed_transcript
  ENST00000524764 SGK1-029 134172600-134173345 retained_intron
  ENST00000524929 SGK1-002 134259793-134317629 protein_coding
  ENST00000525700 SGK1-006 134173801-134177847 retained_intron
  ENST00000525877 SGK1-015 134171365-134172739 retained_intron
  ENST00000528577 SGK1-017 134169881-134177905 protein_coding
  ENST00000530421 SGK1-025 134173700-134174866 retained_intron
  ENST00000531575 SGK1-023 134173081-134249540 processed_transcript
  ENST00000531782 SGK1-030 134170800-134172297 retained_intron
  ENST00000532021 SGK1-024 134173117-134177860 retained_intron
  ENST00000532856 SGK1-026 134173172-134174861 retained_intron
  ENST00000533224 SGK1-020 134262038-134318112 protein_coding
  ENST00000534658 SGK1-027 134172726-134174868 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000237305ENST00000367855ENST00000367857ENST00000367858ENST00000413996ENST00000474427ENST00000475719ENST00000477460ENST00000489458ENST00000528577
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000237305 6.220±0.00 27.415±0.00 N/A 22.009±0.00 8.225±0.00 4.193±0.00 6.033±0.00 50.126±0.00 39.203±0.00 23.689±0.00 4.646±0.00 58.806±33.67 24.709±5.65 19.174±0.00
ENST00000367855 1.565±0.00 N/A N/A N/A 4.419±0.00 N/A N/A N/A N/A N/A 0.697±0.00 49.077±0.00 N/A N/A
ENST00000367857 2.301±0.00 N/A N/A N/A 6.230±0.00 N/A 5.456±0.00 29.466±0.00 N/A 21.962±0.00 2.029±0.00 6.528±0.00 N/A N/A
ENST00000367858 N/A N/A N/A 4.826±2.38 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000413996 1.860±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.135±0.00 4.132±0.00 N/A
ENST00000474427 N/A 4.985±0.00 1.241±0.00 0.796±0.00 1.371±0.00 1.276±0.00 0.592±0.00 N/A 0.777±0.00 3.739±0.00 N/A 7.895±1.07 N/A N/A
ENST00000475719 N/A N/A 3.327±0.00 4.791±0.00 3.642±0.00 N/A N/A 2.488±0.00 2.053±0.00 N/A 0.986±0.00 13.633±0.00 22.756±0.00 N/A
ENST00000477460 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 35.408±1.11 42.787±0.00 18.084±0.00
ENST00000489458 N/A N/A 10.856±0.00 N/A 6.472±0.00 4.839±0.00 N/A 6.889±0.00 4.205±0.00 N/A 1.583±0.00 26.054±0.00 N/A N/A
ENST00000528577 N/A N/A N/A N/A N/A 2.071±0.00 N/A N/A N/A N/A N/A 9.630±0.00 N/A 8.146±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00014S CIL_00014S_0002 CGP 6:133988697-134318112
CIL_00014R CIL_00014R_0002 CGP 6:134169246-134950122

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001558 TAS regulation of cell growth
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004712 IDA protein serine/threonine/tyrosine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005246 TAS calcium channel regulator activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005783 IEA endoplasmic reticulum
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0006814 TAS sodium ion transport
GO:0006915 IEA apoptotic process
GO:0006950 TAS response to stress
GO:0006974 IEA cellular response to DNA damage stimulus
GO:0007616 TAS long-term memory
GO:0008217 TAS regulation of blood pressure
GO:0015459 TAS potassium channel regulator activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0017080 TAS sodium channel regulator activity
GO:0017081 TAS chloride channel regulator activity
GO:0030334 TAS regulation of cell migration
GO:0032411 TAS positive regulation of transporter activity
GO:0034220 TAS ion transmembrane transport
GO:0035091 IEA phosphatidylinositol binding
GO:0042127 TAS regulation of cell proliferation
GO:0042981 TAS regulation of apoptotic process
GO:0050790 TAS regulation of catalytic activity
GO:0051090 TAS regulation of sequence-specific DNA binding transcription factor activity
GO:0055085 TAS transmembrane transport
GO:0060453 TAS regulation of gastric acid secretion
GO:0070294 TAS renal sodium ion absorption

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000025522 sgk1 serum/glucocorticoid regulated kinase 1 protein_coding Danio_rerio
ENSMUSG00000019970 Sgk1 serum/glucocorticoid regulated kinase 1 protein_coding Mus_musculus

Loading