C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serum/glucocorticoid regulated kinase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000019970 Sgk1 10090 + 10:21882184-21999903 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020145 Sgk1-001 21994666-21999903 protein_coding
  ENSMUST00000092673 Sgk1-003 21993890-21999891 protein_coding
  ENSMUST00000100036 Sgk1-201 21992223-21999898 protein_coding
  ENSMUST00000120509 Sgk1-002 21882184-21999893 protein_coding
  ENSMUST00000124203 Sgk1-005 21928470-21990402 protein_coding
  ENSMUST00000124350 Sgk1-008 21994910-21997434 protein_coding
  ENSMUST00000126560 Sgk1-010 21994711-21996341 retained_intron
  ENSMUST00000135195 Sgk1-011 21996591-21998240 retained_intron
  ENSMUST00000141218 Sgk1-009 21994683-21995601 retained_intron
  ENSMUST00000142174 Sgk1-006 21978672-21995893 protein_coding
  ENSMUST00000143094 Sgk1-004 21882369-21899145 processed_transcript
  ENSMUST00000150089 Sgk1-007 21992223-21995874 protein_coding
  ENSMUST00000164659 Sgk1-202 21978672-21999898 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020145ENSMUST00000092673ENSMUST00000100036ENSMUST00000120509ENSMUST00000124350ENSMUST00000135195ENSMUST00000141218ENSMUST00000142174ENSMUST00000164659
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020145 12.595±0.77 8.100±2.99 13.715±2.27 5.093±0.44 14.417±2.76 52.206±8.94 11.525±1.13 37.052±2.39 4.941±1.12 42.290±5.77 67.881±12.55 44.013±16.38 23.338±25.01 1.829±0.40
ENSMUST00000092673 3.489±1.53 3.550±0.98 2.899±0.14 N/A 2.716±1.03 N/A 2.937±0.42 4.691±0.59 0.858±0.31 6.086±0.45 N/A N/A 7.743±0.00 0.234±0.16
ENSMUST00000100036 N/A 4.564±1.85 N/A N/A N/A N/A N/A N/A 1.364±0.47 N/A N/A N/A N/A N/A
ENSMUST00000120509 N/A N/A N/A 3.434±0.76 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000124350 N/A N/A N/A 8.438±0.00 N/A N/A N/A N/A N/A N/A N/A 42.327±0.00 16.604±6.94 0.389±0.00
ENSMUST00000135195 N/A N/A N/A 21.467±0.00 N/A N/A N/A N/A N/A N/A N/A 47.534±43.66 59.580±26.23 1.341±0.00
ENSMUST00000141218 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 181.830±0.00 N/A N/A
ENSMUST00000142174 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.776±0.00
ENSMUST00000164659 N/A 6.085±1.22 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.566±0.07

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IDA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004712 ISO protein serine/threonine/tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005783 IEA endoplasmic reticulum
GO:0005886 IEA plasma membrane
GO:0006468 IDA protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0006974 IDA cellular response to DNA damage stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000025522 sgk1 serum/glucocorticoid regulated kinase 1 protein_coding Danio_rerio
ENSG00000118515 SGK1 serum/glucocorticoid regulated kinase 1 protein_coding Homo_sapiens

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