C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Kruppel-like factor 12
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000118922 KLF12 9606 - 13:73686089-74133905 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000377666 KLF12-201 73695490-74133905 protein_coding
  ENST00000377669 KLF12-001 73686089-73995049 protein_coding
  ENST00000472022 KLF12-002 73812873-73995056 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000377666ENST00000377669ENST00000472022
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000377666 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.268±0.00 N/A N/A N/A
ENST00000377669 0.509±0.00 2.480±0.00 2.035±0.00 1.486±0.00 1.013±0.00 1.600±0.71 1.922±0.00 3.005±0.93 2.460±0.95 0.977±0.00 0.838±0.16 0.903±0.45 0.165±0.02 0.814±0.00
ENST00000472022 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.164±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00051S CIL_00051S_0001 CGP 13:73054976-74133905

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000977 IEA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001227 IEA RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003714 TAS transcription corepressor activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 TAS regulation of transcription from RNA polymerase II promoter
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015312 klf12a Kruppel-like factor 12a protein_coding Danio_rerio
ENSDARG00000032197 klf12b Kruppel-like factor 12b protein_coding Danio_rerio
ENSMUSG00000072294 Klf12 Kruppel-like factor 12 protein_coding Mus_musculus

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