C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: apoptosis resistant E3 ubiquitin protein ligase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000119682 AREL1 9606 - 14:74653437-74713115 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000356357 AREL1-001 74661252-74713115 protein_coding
  ENST00000469797 AREL1-003 74670642-74713067 retained_intron
  ENST00000473934 AREL1-004 74691059-74713087 processed_transcript
  ENST00000481010 AREL1-018 74669687-74675708 nonsense_mediated_decay
  ENST00000490805 AREL1-017 74673184-74676215 protein_coding
  ENST00000553279 AREL1-021 74675866-74685646 nonsense_mediated_decay
  ENST00000553411 AREL1-016 74675788-74683395 nonsense_mediated_decay
  ENST00000554070 AREL1-020 74653437-74664065 nonsense_mediated_decay
  ENST00000554525 AREL1-015 74692016-74712943 processed_transcript
  ENST00000555249 AREL1-014 74683389-74713080 protein_coding
  ENST00000555330 AREL1-012 74661272-74685660 nonsense_mediated_decay
  ENST00000556202 AREL1-007 74663814-74713087 protein_coding
  ENST00000556327 AREL1-005 74670071-74676024 retained_intron
  ENST00000556589 AREL1-011 74683296-74713098 processed_transcript
  ENST00000556860 AREL1-013 74692102-74713087 processed_transcript
  ENST00000557401 AREL1-009 74660221-74713108 processed_transcript
  ENST00000557688 AREL1-019 74663671-74664954 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000356357ENST00000469797ENST00000481010ENST00000555330ENST00000556202ENST00000556327
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000356357 2.328±0.00 1.432±0.00 2.355±0.00 3.422±1.01 1.305±0.06 0.697±0.00 2.059±0.88 2.027±0.00 1.410±0.20 1.813±0.33 1.526±0.00 1.962±1.64 1.863±0.77 3.263±1.00
ENST00000469797 N/A N/A N/A N/A 1.394±0.00 2.041±0.00 N/A N/A N/A N/A N/A 1.605±0.00 N/A N/A
ENST00000481010 N/A N/A N/A N/A N/A N/A N/A 2.901±0.00 N/A N/A N/A N/A N/A N/A
ENST00000555330 1.104±0.00 N/A N/A 0.955±0.29 0.670±0.00 3.033±0.00 1.279±0.00 2.695±0.91 1.139±0.00 1.308±0.19 1.705±0.00 1.059±0.00 2.422±0.00 3.948±0.37
ENST00000556202 N/A N/A N/A N/A 1.045±0.00 N/A N/A N/A N/A N/A 0.533±0.00 0.722±0.00 N/A N/A
ENST00000556327 N/A N/A N/A N/A N/A N/A 2.045±0.00 N/A N/A N/A 2.577±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005AZ CIL_0005AZ_0001 CGP 14:74653437-74738620

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004842 IEA:IBA ubiquitin-protein transferase activity
GO:0005634 IBA nucleus
GO:0005737 IBA cytoplasm
GO:0005829 IDA cytosol
GO:0006915 IEA apoptotic process
GO:0016567 IEA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0042787 IBA protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043066 IDA negative regulation of apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000090858 AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 protein_coding Danio_rerio
ENSMUSG00000042350 Arel1 apoptosis resistant E3 ubiquitin protein ligase 1 protein_coding Mus_musculus

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