C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: secreted frizzled-related protein 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000120057 SFRP5 9606 - 10:97766751-97771952 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000266066 SFRP5-001 97766751-97771952 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryTestisENST00000266066
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Testis
ENST00000266066 5.123±0.00 0.275±0.00 0.120±0.00 0.920±0.00 0.297±0.08 34.519±0.00 0.524±0.41 0.454±0.24 6.125±5.75 0.584±0.49 0.764±0.15 0.189±0.00 1.304±0.66

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004V8 CIL_0004V8_0001 CGP 10:97737121-97771952
CIL_0004V9 CIL_0004V9_0001 CGP 10:97766751-97871580

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001944 IBA vasculature development
GO:0005515 IEA protein binding
GO:0005615 TAS extracellular space
GO:0005737 IBA cytoplasm
GO:0005886 IBA plasma membrane
GO:0006915 TAS apoptotic process
GO:0007163 TAS establishment or maintenance of cell polarity
GO:0007165 TAS signal transduction
GO:0007420 IBA brain development
GO:0007601 TAS visual perception
GO:0008285 IMP negative regulation of cell proliferation
GO:0008406 IBA gonad development
GO:0009653 TAS anatomical structure morphogenesis
GO:0017147 IBA Wnt-protein binding
GO:0030154 IEA cell differentiation
GO:0030165 IBA PDZ domain binding
GO:0035414 IMP negative regulation of catenin import into nucleus
GO:0036342 IEA post-anal tail morphogenesis
GO:0042813 IBA Wnt-activated receptor activity
GO:0043433 IMP negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043508 IEA negative regulation of JUN kinase activity
GO:0048546 IEA digestive tract morphogenesis
GO:0051898 IMP negative regulation of protein kinase B signaling
GO:0060028 IEA convergent extension involved in axis elongation
GO:0090090 IMP negative regulation of canonical Wnt signaling pathway
GO:0090175 IEA regulation of establishment of planar polarity
GO:0090179 IEA planar cell polarity pathway involved in neural tube closure
GO:2000041 IEA negative regulation of planar cell polarity pathway involved in axis elongation
GO:2000057 IMP negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039041 sfrp5 secreted frizzled-related protein 5 protein_coding Danio_rerio
ENSMUSG00000018822 Sfrp5 secreted frizzled-related sequence protein 5 protein_coding Mus_musculus

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