C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: secreted frizzled-related sequence protein 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000018822 Sfrp5 10090 - 19:42197971-42202252 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000018966 Sfrp5-001 42197971-42202252 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000018966
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000018966 20.920±20.03 5.175±1.92 5.802±0.01 1.553±0.16 9.412±3.82 2.463±0.45 5.534±0.97 1.673±0.30 0.035±0.02 2.584±0.80 2.409±0.73 0.829±0.40 7.039±5.27 0.079±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004V8 CIL_0004V8_0002 CGP 19:42163951-42202252
CIL_0004V9 CIL_0004V9_0002 CGP 19:42197971-42270348

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001944 IBA vasculature development
GO:0005576 IEA extracellular region
GO:0005737 IBA cytoplasm
GO:0005886 IBA plasma membrane
GO:0006357 IBA regulation of transcription from RNA polymerase II promoter
GO:0007420 IBA brain development
GO:0008285 IEA negative regulation of cell proliferation
GO:0008406 IBA gonad development
GO:0017147 IBA Wnt-protein binding
GO:0030154 IEA cell differentiation
GO:0030165 IBA PDZ domain binding
GO:0035414 IEA negative regulation of catenin import into nucleus
GO:0036342 IGI post-anal tail morphogenesis
GO:0042813 IBA Wnt-activated receptor activity
GO:0043433 IEA negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043508 IGI negative regulation of JUN kinase activity
GO:0048546 IGI digestive tract morphogenesis
GO:0051898 IEA negative regulation of protein kinase B signaling
GO:0060028 IGI convergent extension involved in axis elongation
GO:0060070 IBA canonical Wnt signaling pathway
GO:0090090 IEA negative regulation of canonical Wnt signaling pathway
GO:0090175 IGI regulation of establishment of planar polarity
GO:0090179 IGI planar cell polarity pathway involved in neural tube closure
GO:2000041 IGI negative regulation of planar cell polarity pathway involved in axis elongation
GO:2000057 IEA negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039041 sfrp5 secreted frizzled-related protein 5 protein_coding Danio_rerio
ENSG00000120057 SFRP5 secreted frizzled-related protein 5 protein_coding Homo_sapiens

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