C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dual specificity phosphatase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000120129 DUSP1 9606 - 5:172768090-172771195 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000239223 DUSP1-001 172768090-172771195 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000239223
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000239223 332.296±0.00 39.167±0.00 22.093±0.00 18.414±7.13 145.171±98.15 59.535±55.03 28.172±16.86 57.771±48.20 26.614±6.23 325.010±244.29 62.176±41.79 238.724±297.78 276.569±58.26 96.085±55.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008KN CIL_0008KN_0001 VISTA 5:172471670-173074006
CIL_0000OU CIL_0000OU_0002 CGP 5:172641266-172771195
CIL_0000OT CIL_0000OT_0002 CGP 5:172768090-172952685

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000188 ISS inactivation of MAPK activity
GO:0001706 IBA endoderm formation
GO:0004725 IEA protein tyrosine phosphatase activity
GO:0004726 TAS non-membrane spanning protein tyrosine phosphatase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006470 IBA:IEA protein dephosphorylation
GO:0006979 TAS response to oxidative stress
GO:0008138 IBA:IEA protein tyrosine/serine/threonine phosphatase activity
GO:0008330 IEA protein tyrosine/threonine phosphatase activity
GO:0009416 IEA response to light stimulus
GO:0010033 IEA response to organic substance
GO:0016311 IEA dephosphorylation
GO:0016791 IEA phosphatase activity
GO:0017017 ISS:IEA MAP kinase tyrosine/serine/threonine phosphatase activity
GO:0032355 IEA response to estradiol
GO:0032526 IEA response to retinoic acid
GO:0032870 IEA cellular response to hormone stimulus
GO:0033574 IEA response to testosterone
GO:0035335 ISS peptidyl-tyrosine dephosphorylation
GO:0035556 IEA intracellular signal transduction
GO:0035970 ISS peptidyl-threonine dephosphorylation
GO:0042542 IEA response to hydrogen peroxide
GO:0042981 IBA regulation of apoptotic process
GO:0043065 IEA positive regulation of apoptotic process
GO:0043066 IEA negative regulation of apoptotic process
GO:0043407 IDA negative regulation of MAP kinase activity
GO:0043409 ISS negative regulation of MAPK cascade
GO:0051384 IEA response to glucocorticoid
GO:0051447 ISS negative regulation of meiotic cell cycle
GO:0051591 IEA response to cAMP
GO:0051592 IEA response to calcium ion
GO:0070373 IEA negative regulation of ERK1 and ERK2 cascade
GO:0071850 ISS mitotic cell cycle arrest
GO:0090266 ISS regulation of mitotic cell cycle spindle assembly checkpoint
GO:2000279 IEA negative regulation of DNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007628 dusp1 dual specificity phosphatase 1 protein_coding Danio_rerio
ENSMUSG00000024190 Dusp1 dual specificity phosphatase 1 protein_coding Mus_musculus

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