C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein-L-isoaspartate (D-aspartate) O-methyltransferase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000120265 PCMT1 9606 + 6:149749443-149811420 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000367378 PCMT1-004 149749444-149802530 protein_coding
  ENST00000367380 PCMT1-201 149749695-149811420 protein_coding
  ENST00000367384 PCMT1-001 149749443-149811420 protein_coding
  ENST00000460828 PCMT1-006 149749727-149773150 nonsense_mediated_decay
  ENST00000464889 PCMT1-002 149749444-149811420 protein_coding
  ENST00000480010 PCMT1-005 149810040-149810908 processed_transcript
  ENST00000484601 PCMT1-003 149749444-149796433 nonsense_mediated_decay
  ENST00000486585 PCMT1-007 149749816-149793669 nonsense_mediated_decay
  ENST00000494411 PCMT1-009 149749727-149790056 nonsense_mediated_decay
  ENST00000495487 PCMT1-008 149750044-149793632 protein_coding
  ENST00000544496 PCMT1-202 149749695-149811420 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000367378ENST00000367380ENST00000367384ENST00000464889ENST00000484601ENST00000544496
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000367378 18.059±0.00 12.810±0.00 1.814±0.00 28.243±6.72 12.053±3.65 4.829±0.00 7.612±0.00 10.536±0.00 10.737±0.67 11.761±0.00 20.880±0.00 19.187±0.00 12.510±2.88 27.321±8.77
ENST00000367380 N/A N/A 1.335±0.00 N/A N/A 1.641±0.00 2.103±0.00 8.074±0.00 6.352±0.00 3.893±0.73 N/A 27.126±17.36 12.456±0.00 N/A
ENST00000367384 9.008±0.00 5.951±0.00 N/A 13.424±4.13 9.903±0.00 9.238±7.10 N/A 11.600±0.00 6.119±0.65 5.383±0.27 5.975±0.00 14.509±1.01 10.289±0.72 12.940±0.00
ENST00000464889 N/A N/A N/A 29.189±0.00 N/A N/A 19.417±17.11 7.292±0.00 N/A 3.064±1.02 9.998±7.39 11.285±3.77 6.622±1.25 N/A
ENST00000484601 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 51.108±0.00 N/A 29.831±0.00
ENST00000544496 9.666±0.00 10.303±0.00 N/A 39.356±28.75 17.378±0.00 19.189±0.00 N/A 8.106±0.00 2.661±0.00 N/A 15.745±0.00 11.215±0.00 N/A 19.380±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004719 TAS:IEA protein-L-isoaspartate (D-aspartate) O-methyltransferase activity
GO:0005737 IDA cytoplasm
GO:0005783 TAS endoplasmic reticulum
GO:0006464 IEA cellular protein modification process
GO:0006479 TAS protein methylation
GO:0008757 IEA S-adenosylmethionine-dependent methyltransferase activity
GO:0030091 TAS protein repair
GO:0031982 IDA vesicle
GO:0046498 IEA S-adenosylhomocysteine metabolic process
GO:0046500 IEA S-adenosylmethionine metabolic process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015201 pcmt l-isoaspartyl protein carboxyl methyltransferase protein_coding Danio_rerio
ENSMUSG00000019795 Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 protein_coding Mus_musculus

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