C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein-L-isoaspartate (D-aspartate) O-methyltransferase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000019795 Pcmt1 10090 - 10:7629373-7681136 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000159835 Pcmt1-010 7647594-7651536 nonsense_mediated_decay
  ENSMUST00000159917 Pcmt1-002 7629381-7663303 protein_coding
  ENSMUST00000159977 Pcmt1-009 7647619-7681130 protein_coding
  ENSMUST00000160250 Pcmt1-003 7639659-7663608 retained_intron
  ENSMUST00000160517 Pcmt1-007 7648965-7663264 retained_intron
  ENSMUST00000161123 Pcmt1-006 7629373-7663264 nonsense_mediated_decay
  ENSMUST00000161428 Pcmt1-005 7637730-7649155 protein_coding
  ENSMUST00000162606 Pcmt1-001 7629373-7663608 protein_coding
  ENSMUST00000162682 Pcmt1-008 7644332-7681136 protein_coding
  ENSMUST00000163085 Pcmt1-004 7637730-7663261 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000159917ENSMUST00000159977ENSMUST00000160250ENSMUST00000160517ENSMUST00000161123ENSMUST00000161428ENSMUST00000162606ENSMUST00000162682ENSMUST00000163085
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000159917 4.271±1.49 4.196±0.00 14.083±1.44 18.206±3.00 5.797±1.54 6.409±1.16 8.398±0.99 4.161±0.49 7.345±4.43 8.214±1.80 36.278±1.27 4.971±1.76 5.347±1.48 18.443±1.98
ENSMUST00000159977 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.272±0.30 N/A N/A
ENSMUST00000160250 N/A 6.602±2.51 N/A N/A 5.236±0.77 9.229±2.47 N/A 10.756±1.27 6.805±2.03 N/A N/A 5.168±1.69 N/A 26.396±0.00
ENSMUST00000160517 N/A 26.255±9.16 N/A N/A 12.942±0.12 12.153±0.00 N/A N/A N/A 16.789±2.39 N/A 8.967±1.42 N/A 99.424±0.00
ENSMUST00000161123 N/A N/A N/A N/A N/A N/A N/A N/A 1.985±0.00 N/A N/A 1.814±0.00 1.856±0.08 N/A
ENSMUST00000161428 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 22.653±0.00
ENSMUST00000162606 3.489±0.52 2.274±0.58 7.225±0.41 5.920±0.23 3.277±0.40 1.957±0.16 2.488±0.51 7.502±1.33 4.749±1.72 2.658±0.52 N/A 3.136±1.24 3.912±1.99 12.485±1.13
ENSMUST00000162682 N/A 11.679±5.03 N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.341±0.00 N/A N/A
ENSMUST00000163085 7.903±0.44 N/A 9.620±2.55 20.324±9.88 4.890±0.00 N/A 10.033±1.31 8.290±0.25 25.038±9.21 6.508±0.37 N/A 7.964±3.15 16.867±3.73 70.535±22.66

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005X2 CIL_0005X2_0002 CGP 10:7589800-7681136
CIL_00050T CIL_00050T_0002 CGP 10:7629373-7681136

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004719 IDA protein-L-isoaspartate (D-aspartate) O-methyltransferase activity
GO:0005737 IEA cytoplasm
GO:0006479 IDA protein methylation
GO:0008757 IEA S-adenosylmethionine-dependent methyltransferase activity
GO:0046498 IEA S-adenosylhomocysteine metabolic process
GO:0046500 IEA S-adenosylmethionine metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015201 pcmt l-isoaspartyl protein carboxyl methyltransferase protein_coding Danio_rerio
ENSG00000120265 PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase protein_coding Homo_sapiens

Loading