C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tumor necrosis factor receptor superfamily, member 10b
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000120889 TNFRSF10B 9606 - 8:23020133-23069179 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000276431 TNFRSF10B-001 23020133-23069179 protein_coding
  ENST00000347739 TNFRSF10B-002 23022311-23069021 protein_coding
  ENST00000518531 TNFRSF10B-007 23028265-23030872 retained_intron
  ENST00000519028 TNFRSF10B-005 23042904-23069022 retained_intron
  ENST00000519910 TNFRSF10B-006 23028540-23049927 processed_transcript
  ENST00000520109 TNFRSF10B-008 23022886-23027634 retained_intron
  ENST00000523504 TNFRSF10B-003 23022474-23069031 nonsense_mediated_decay
  ENST00000523752 TNFRSF10B-004 23020133-23027968 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000276431ENST00000347739ENST00000519028ENST00000523504ENST00000523752
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000276431 6.994±0.00 5.646±0.00 0.706±0.00 4.025±0.00 2.705±1.32 3.099±0.00 3.349±0.44 2.494±1.01 8.618±5.16 N/A 5.635±1.45 3.284±0.42 1.899±0.00
ENST00000347739 N/A N/A N/A 3.606±0.00 1.176±0.00 N/A 2.088±0.00 N/A N/A N/A 4.509±0.00 N/A N/A
ENST00000519028 N/A N/A 10.768±0.00 9.673±0.00 N/A N/A N/A 11.066±0.00 N/A N/A 17.118±0.00 N/A N/A
ENST00000523504 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 17.611±0.00 N/A N/A
ENST00000523752 4.293±0.00 5.255±0.00 N/A 1.974±0.19 1.926±0.00 N/A N/A 2.340±0.00 6.152±0.00 2.534±0.00 4.572±1.62 2.456±0.16 2.347±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004872 NAS receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005886 TAS plasma membrane
GO:0006915 NAS apoptotic process
GO:0006919 TAS activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007165 IEA signal transduction
GO:0007166 TAS cell surface receptor signaling pathway
GO:0007250 NAS activation of NF-kappaB-inducing kinase activity
GO:0008625 NAS extrinsic apoptotic signaling pathway via death domain receptors
GO:0016021 IC integral component of membrane
GO:0034976 IDA response to endoplasmic reticulum stress
GO:0042981 NAS regulation of apoptotic process
GO:0043123 IEP positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045569 NAS:IEA TRAIL binding
GO:0070059 IMP intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0071260 IEP cellular response to mechanical stimulus
GO:0097190 TAS apoptotic signaling pathway
GO:2001239 TAS regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004392 hdr hematopoietic death receptor protein_coding Danio_rerio
ENSDARG00000004451 tnfrsfa tumor necrosis factor receptor superfamily, member a protein_coding Danio_rerio
ENSMUSG00000022074 Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b protein_coding Mus_musculus

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