C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: tumor necrosis factor receptor superfamily, member 10b
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000276431 TNFRSF10B-001 ENSG00000120889 9606 - 8:23020133-23069179 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000276431
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000276431 6.994±0.00 5.646±0.00 0.706±0.00 4.025±0.00 2.705±1.32 3.099±0.00 3.349±0.44 2.494±1.01 8.618±5.16 5.635±1.45 3.284±0.42 1.899±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004872 NAS receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005886 TAS plasma membrane
GO:0006915 NAS apoptotic process
GO:0006919 TAS activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007165 IEA signal transduction
GO:0007166 TAS cell surface receptor signaling pathway
GO:0007250 NAS activation of NF-kappaB-inducing kinase activity
GO:0008625 NAS extrinsic apoptotic signaling pathway via death domain receptors
GO:0016021 IC integral component of membrane
GO:0034976 IDA response to endoplasmic reticulum stress
GO:0042981 NAS regulation of apoptotic process
GO:0043123 IEP positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045569 NAS:IEA TRAIL binding
GO:0070059 IMP intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0071260 IEP cellular response to mechanical stimulus
GO:0097190 TAS apoptotic signaling pathway
GO:2001239 TAS regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000022665 Rhobtb2-201 protein_coding Mus_musculus 1e-17 97
ENSMUST00000030893 Dffb-001 protein_coding Mus_musculus 0.00008 55

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