C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000121207 LRAT 9606 + 4:154626945-154753118 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000336356 LRAT-005 154743971-154753118 protein_coding
  ENST00000499392 LRAT-001 154627072-154748320 processed_transcript
  ENST00000500890 LRAT-003 154626945-154699900 processed_transcript
  ENST00000502474 LRAT-007 154745374-154749420 processed_transcript
  ENST00000502525 LRAT-002 154626961-154744533 protein_coding
  ENST00000507827 LRAT-004 154740838-154751035 protein_coding
  ENST00000510733 LRAT-006 154744000-154753118 retained_intron
  ENST00000510919 LRAT-008 154745447-154749180 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENST00000336356ENST00000500890ENST00000502474ENST00000507827ENST00000510733
Transcript ID Bladder Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENST00000336356 N/A N/A N/A 0.014±0.00 0.027±0.00 0.144±0.00 0.159±0.15 0.010±0.00 0.037±0.00 0.004±0.00 0.288±0.00
ENST00000500890 N/A N/A N/A N/A 0.023±0.00 0.215±0.00 N/A N/A N/A N/A N/A
ENST00000502474 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.026±0.00 N/A
ENST00000507827 0.022±0.00 N/A N/A N/A N/A 0.528±0.00 N/A N/A N/A 0.007±0.00 N/A
ENST00000510733 N/A 0.377±0.00 0.211±0.00 0.244±0.00 N/A N/A N/A 0.002±0.00 0.231±0.22 0.004±0.00 0.523±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008D1 CIL_0008D1_0001 VISTA 4:154359551-154960904
CIL_0000OJ CIL_0000OJ_0002 CGP 4:154626945-154828813

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001523 TAS retinoid metabolic process
GO:0001972 IEA retinoic acid binding
GO:0005771 ISS multivesicular body
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005791 ISS rough endoplasmic reticulum
GO:0006776 IEA vitamin A metabolic process
GO:0007601 IEA visual perception
GO:0007603 TAS phototransduction, visible light
GO:0008374 IEA O-acyltransferase activity
GO:0016021 IEA integral component of membrane
GO:0016746 TAS transferase activity, transferring acyl groups
GO:0019841 IEA retinol binding
GO:0032370 IEA positive regulation of lipid transport
GO:0042572 IEA retinol metabolic process
GO:0042573 IEA retinoic acid metabolic process
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0047173 IEA phosphatidylcholine-retinol O-acyltransferase activity
GO:0048471 ISS perinuclear region of cytoplasm

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077652 LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) protein_coding Danio_rerio
ENSMUSG00000028003 Lrat lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase) protein_coding Mus_musculus

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