C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: plasminogen activator, urokinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000122861 PLAU 9606 + 10:73909177-73917497 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000372764 PLAU-001 73911157-73917497 protein_coding
  ENST00000446342 PLAU-201 73911104-73917496 protein_coding
  ENST00000481390 PLAU-004 73909177-73913049 protein_coding
  ENST00000494287 PLAU-007 73911147-73913753 processed_transcript
  ENST00000496926 PLAU-005 73910605-73911539 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000372764
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000372764 5.272±0.00 9.652±0.00 6.268±0.00 0.460±0.30 4.281±2.99 5.055±0.00 3.704±0.00 7.278±7.25 0.333±0.00 3.935±1.92 1.482±0.82 9.601±6.88 27.827±5.87 4.387±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001GS CIL_0001GS_0001 CGP 10:73812501-73917497

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IEA response to hypoxia
GO:0003824 IEA catalytic activity
GO:0004252 TAS:IEA serine-type endopeptidase activity
GO:0005515 IPI:IEA protein binding
GO:0005576 TAS extracellular region
GO:0005615 IDA extracellular space
GO:0005886 TAS plasma membrane
GO:0005925 IDA focal adhesion
GO:0006508 IEA proteolysis
GO:0006935 TAS chemotaxis
GO:0007165 TAS signal transduction
GO:0007596 TAS blood coagulation
GO:0009986 IDA cell surface
GO:0010469 IDA regulation of receptor activity
GO:0014909 IEA smooth muscle cell migration
GO:0014910 IDA regulation of smooth muscle cell migration
GO:0033628 IDA regulation of cell adhesion mediated by integrin
GO:0042127 IEA regulation of cell proliferation
GO:0042730 TAS fibrinolysis
GO:0061041 IC regulation of wound healing
GO:0070062 IDA extracellular vesicular exosome
GO:2000097 IDA regulation of smooth muscle cell-matrix adhesion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039145 plaub plasminogen activator, urokinase b protein_coding Danio_rerio
ENSDARG00000075265 plaua plasminogen activator, urokinase a protein_coding Danio_rerio
ENSMUSG00000021822 Plau plasminogen activator, urokinase protein_coding Mus_musculus

Loading