C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: plasminogen activator, urokinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021822 Plau 10090 + 14:20836662-20843388 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000022368 Plau-201 20836662-20843388 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000022368
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000022368 17.700±10.72 1.855±0.18 36.053±2.06 0.615±0.18 12.158±2.78 5.064±0.96 0.963±0.23 153.979±5.87 0.705±0.49 2.540±1.46 5.250±1.25 22.939±9.12 21.256±6.60 0.568±0.22

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001GS CIL_0001GS_0002 CGP 14:20734875-20843388

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IMP response to hypoxia
GO:0004252 IEA serine-type endopeptidase activity
GO:0005615 IEA extracellular space
GO:0005925 IEA focal adhesion
GO:0006508 IEA proteolysis
GO:0009986 IEA cell surface
GO:0010469 IEA regulation of receptor activity
GO:0014909 IMP smooth muscle cell migration
GO:0014910 IEA regulation of smooth muscle cell migration
GO:0033628 IEA regulation of cell adhesion mediated by integrin
GO:0042127 IGI regulation of cell proliferation
GO:0042730 IMP fibrinolysis
GO:0070062 IEA extracellular vesicular exosome
GO:2000097 IEA regulation of smooth muscle cell-matrix adhesion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039145 plaub plasminogen activator, urokinase b protein_coding Danio_rerio
ENSDARG00000075265 plaua plasminogen activator, urokinase a protein_coding Danio_rerio
ENSG00000122861 PLAU plasminogen activator, urokinase protein_coding Homo_sapiens

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