C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000124198 ARFGEF2 9606 + 20:48921890-49036693 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000371917 ARFGEF2-001 48921890-49036693 protein_coding
  ENST00000493140 ARFGEF2-002 48998100-48998446 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000371917
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000371917 2.807±0.00 1.076±0.00 3.181±0.00 5.154±3.32 5.856±0.73 4.977±1.15 5.657±2.55 2.606±0.57 3.231±1.23 1.875±0.00 2.605±1.08 5.804±1.54 2.384±0.88 8.393±0.09

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001XQ CIL_0001XQ_0001 CGP 20:48921890-49096960

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 IDA Golgi membrane
GO:0001881 IDA receptor recycling
GO:0005085 IDA guanyl-nucleotide exchange factor activity
GO:0005086 IBA:IEA ARF guanyl-nucleotide exchange factor activity
GO:0005488 IEA binding
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005802 ISS trans-Golgi network
GO:0005815 IDA microtubule organizing center
GO:0005829 IDA cytosol
GO:0005879 ISS axonemal microtubule
GO:0006887 IEA exocytosis
GO:0006893 IMP Golgi to plasma membrane transport
GO:0007032 IMP endosome organization
GO:0010256 IMP endomembrane system organization
GO:0015031 IEA protein transport
GO:0016020 IDA membrane
GO:0016192 IBA vesicle-mediated transport
GO:0017022 IEA myosin binding
GO:0030054 IEA cell junction
GO:0031410 ISS cytoplasmic vesicle
GO:0032012 IEA regulation of ARF protein signal transduction
GO:0032279 ISS asymmetric synapse
GO:0032280 ISS symmetric synapse
GO:0032760 IMP positive regulation of tumor necrosis factor production
GO:0034237 IDA protein kinase A regulatory subunit binding
GO:0035556 IDA intracellular signal transduction
GO:0043197 ISS dendritic spine
GO:0043547 IEA positive regulation of GTPase activity
GO:0050811 ISS GABA receptor binding
GO:0055037 IDA recycling endosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063474 arfgef1 ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) protein_coding Danio_rerio
ENSMUSG00000074582 Arfgef2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) protein_coding Mus_musculus

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