C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: IQ motif and Sec7 domain 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000124313 IQSEC2 9606 - X:53232876-53321324 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000375365 IQSEC2-009 53234110-53281614 protein_coding
  ENST00000396435 IQSEC2-012 53232876-53321324 protein_coding
  ENST00000462054 IQSEC2-013 53266329-53281594 processed_transcript
  ENST00000485377 IQSEC2-011 53266329-53281594 processed_transcript
  ENST00000498281 IQSEC2-010 53266329-53281594 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000375365ENST00000396435ENST00000462054ENST00000485377ENST00000498281
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000375365 N/A N/A N/A N/A N/A N/A 0.160±0.00 N/A 0.485±0.00 N/A 0.238±0.00 0.332±0.22 1.213±0.00 2.989±1.54
ENST00000396435 N/A N/A N/A 8.714±5.05 0.093±0.00 N/A 0.667±0.00 1.436±0.00 N/A 0.765±0.00 3.238±0.00 0.932±0.65 N/A 0.674±0.00
ENST00000462054 3.788±0.00 2.372±0.00 0.808±0.00 N/A 4.357±0.00 4.718±0.00 1.812±0.00 N/A 0.321±0.00 N/A 6.034±4.07 1.403±0.00 1.784±0.00 N/A
ENST00000485377 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.469±0.00 N/A 0.638±0.00 N/A N/A
ENST00000498281 N/A N/A N/A N/A 3.669±0.00 N/A 1.026±0.81 6.814±0.00 N/A 3.384±0.00 10.593±0.00 3.310±0.00 3.124±1.01 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005086 IBA:IEA ARF guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0005634 IBA nucleus
GO:0030036 IBA actin cytoskeleton organization
GO:0030054 IBA cell junction
GO:0032012 IEA regulation of ARF protein signal transduction
GO:0043547 IEA positive regulation of GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077709 iqsec2 IQ motif and Sec7 domain 2 protein_coding Danio_rerio
ENSMUSG00000041115 Iqsec2 IQ motif and Sec7 domain 2 protein_coding Mus_musculus

Loading