C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: destrin (actin depolymerizing factor)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000125868 DSTN 9606 + 20:17569863-17609919 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000246069 DSTN-001 17569863-17609919 protein_coding
  ENST00000449141 DSTN-003 17570090-17607222 nonsense_mediated_decay
  ENST00000474024 DSTN-002 17570082-17608242 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000449141ENST00000474024
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000449141 N/A N/A 9.200±0.00 24.497±0.00 N/A 33.373±0.00 66.234±0.00 8.790±0.00 58.857±0.00 21.586±0.00 N/A 28.682±0.00 N/A N/A
ENST00000474024 96.775±0.00 194.084±0.00 22.788±0.00 80.208±25.80 94.941±19.18 290.791±205.93 95.645±57.06 93.718±77.30 109.617±71.22 131.221±80.76 25.307±15.85 165.906±80.15 138.615±11.30 158.254±88.93

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002DJ CIL_0002DJ_0001 CGP 20:17493905-17609919
CIL_0008YD CIL_0008YD_0001 VISTA 20:17559199-18160694
CIL_0002D9 CIL_0002D9_0001 CGP 20:17569863-17682295

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003779 IEA actin binding
GO:0005622 IEA intracellular
GO:0005737 IEA cytoplasm
GO:0006928 IEA cellular component movement
GO:0008154 TAS actin polymerization or depolymerization
GO:0015629 TAS actin cytoskeleton
GO:0030042 IEA actin filament depolymerization
GO:0030836 IEA positive regulation of actin filament depolymerization
GO:0030864 IEA cortical actin cytoskeleton
GO:0051014 TAS actin filament severing
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000015932 Dstn destrin protein_coding Mus_musculus

Loading