C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000125877 ITPA 9606 + 20:3208868-3223870 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000380113 ITPA-002 3209360-3223870 protein_coding
  ENST00000399838 ITPA-007 3209525-3223870 protein_coding
  ENST00000455664 ITPA-009 3209513-3223618 protein_coding
  ENST00000460550 ITPA-006 3209513-3223870 processed_transcript
  ENST00000460676 ITPA-005 3208898-3218596 processed_transcript
  ENST00000461029 ITPA-008 3215212-3223449 processed_transcript
  ENST00000472295 ITPA-001 3221753-3223870 processed_transcript
  ENST00000483354 ITPA-004 3208868-3223870 processed_transcript
  ENST00000490838 ITPA-003 3209489-3223870 processed_transcript
  ENST00000609835 ITPA-010 3209501-3219091 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000380113ENST00000399838ENST00000455664ENST00000460550ENST00000461029ENST00000472295ENST00000609835
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000380113 7.907±0.00 6.658±0.00 N/A 4.504±0.40 5.073±1.96 5.357±2.76 3.178±2.43 10.257±6.90 5.862±4.45 4.212±2.29 0.751±0.00 22.248±11.07 24.182±5.23 6.753±1.20
ENST00000399838 N/A N/A N/A 3.378±0.00 N/A N/A N/A N/A N/A 2.776±0.00 2.332±0.00 N/A N/A 5.123±0.00
ENST00000455664 8.492±0.00 15.797±0.00 N/A 6.002±0.00 11.045±0.00 5.234±0.00 4.178±0.00 16.240±0.00 7.514±0.00 4.893±0.00 3.637±0.00 N/A 10.789±0.86 6.634±0.00
ENST00000460550 3.482±0.00 13.521±0.00 N/A 2.032±0.00 7.152±5.36 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000461029 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 17.291±12.00 12.447±0.00 N/A
ENST00000472295 N/A N/A N/A N/A 2.335±0.00 N/A N/A N/A N/A N/A 1.560±0.48 21.040±0.00 N/A N/A
ENST00000609835 N/A N/A 0.869±0.00 N/A 1.763±0.00 N/A N/A N/A 0.592±0.00 N/A N/A 9.853±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000064 CIL_000064_0001 CGP 20:3190350-3223870
CIL_000065 CIL_000065_0001 CGP 20:3208868-3239190

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0005829 TAS cytosol
GO:0006193 IEA ITP catabolic process
GO:0009204 IEA deoxyribonucleoside triphosphate catabolic process
GO:0016787 IEA hydrolase activity
GO:0035870 EXP dITP diphosphatase activity
GO:0036220 EXP ITP diphosphatase activity
GO:0036222 EXP XTP diphosphatase activity
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding
GO:0047429 IEA nucleoside-triphosphate diphosphatase activity
GO:0051276 IEA chromosome organization
GO:0055086 TAS nucleobase-containing small molecule metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057529 itpa inosine triphosphatase (nucleoside triphosphate pyrophosphatase) protein_coding Danio_rerio
ENSDARG00000091913 ITPA (2 of 2) inosine triphosphatase (nucleoside triphosphate pyrophosphatase) protein_coding Danio_rerio
ENSMUSG00000074797 Itpa inosine triphosphatase (nucleoside triphosphate pyrophosphatase) protein_coding Mus_musculus

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