C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ELK1, member of ETS oncogene family
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000126767 ELK1 9606 - X:47635521-47650604 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000247161 ELK1-001 47635521-47650488 protein_coding
  ENST00000343894 ELK1-201 47635522-47650604 protein_coding
  ENST00000376983 ELK1-002 47636167-47650591 protein_coding
  ENST00000468956 ELK1-004 47648887-47650604 processed_transcript
  ENST00000480157 ELK1-003 47636811-47650591 processed_transcript
  ENST00000592066 ELK1-005 47636167-47650488 protein_coding
  ENST00000619324 ELK1-202 47635522-47650604 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000247161ENST00000343894ENST00000376983ENST00000468956ENST00000592066ENST00000619324
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000247161 4.297±0.00 N/A N/A 2.070±1.22 0.246±0.00 3.325±0.00 N/A N/A N/A 3.511±0.00 N/A 14.999±10.11 2.810±1.12 6.027±0.00
ENST00000343894 N/A N/A N/A N/A N/A 0.629±0.00 0.280±0.00 N/A 2.875±0.00 N/A N/A N/A 2.357±0.00 N/A
ENST00000376983 3.875±0.00 2.077±0.00 0.942±0.00 N/A N/A 2.434±0.00 2.003±1.68 N/A N/A 3.822±0.00 8.411±0.00 8.800±7.08 3.066±0.81 6.456±0.00
ENST00000468956 N/A N/A N/A N/A N/A 0.508±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000592066 3.557±0.00 5.386±0.00 N/A 5.343±2.68 3.482±1.55 1.030±0.57 N/A 2.701±1.45 2.394±1.48 N/A 1.486±0.00 8.724±4.86 4.413±0.00 9.868±6.52
ENST00000619324 N/A 5.408±0.00 N/A 4.437±0.00 2.666±0.00 N/A 5.056±0.00 4.684±0.00 4.685±0.00 2.677±0.00 6.235±0.00 6.437±0.82 5.052±1.85 6.381±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000577 CIL_000577_0001 CGP X:47624213-47650604
CIL_000578 CIL_000578_0001 CGP X:47635521-47659161

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981 IBA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001047 IEA core promoter binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002755 TAS MyD88-dependent toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0003682 IEA chromatin binding
GO:0003690 IEA double-stranded DNA binding
GO:0003700 IEA:IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0005739 IEA mitochondrion
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 IBA transcription from RNA polymerase II promoter
GO:0009416 IEA response to light stimulus
GO:0030154 IBA cell differentiation
GO:0030425 IEA dendrite
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034146 TAS toll-like receptor 5 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0034166 TAS toll-like receptor 10 signaling pathway
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0043025 IEA neuronal cell body
GO:0043565 IEA sequence-specific DNA binding
GO:0043679 IEA axon terminus
GO:0045087 TAS innate immune response
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051403 TAS stress-activated MAPK cascade
GO:0071394 IEA cellular response to testosterone stimulus
GO:0071396 IEA cellular response to lipid
GO:0071480 IEA cellular response to gamma radiation
GO:1901216 IEA positive regulation of neuron death

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078066 elk1 ELK1, member of ETS oncogene family protein_coding Danio_rerio
ENSMUSG00000009406 Elk1 ELK1, member of ETS oncogene family protein_coding Mus_musculus

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