C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Kruppel-like factor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000127528 KLF2 9606 + 19:16324817-16327874 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000248071 KLF2-001 16324817-16327874 protein_coding
  ENST00000592003 KLF2-002 16324840-16327260 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000248071ENST00000592003
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000248071 11.290±0.00 30.910±0.00 0.536±0.00 1.485±0.60 20.539±17.24 1.666±0.92 13.382±12.40 3.935±3.64 4.283±1.07 27.121±24.32 10.653±5.17 63.528±83.90 41.937±12.37 14.800±0.91
ENST00000592003 68.587±0.00 116.876±0.00 N/A 10.259±0.00 97.336±0.00 44.078±0.00 33.181±0.00 15.908±12.56 17.736±0.00 187.052±0.00 50.848±0.00 N/A N/A 50.580±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004DX CIL_0004DX_0002 CGP 19:16324817-16472085

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000902 IEA cell morphogenesis
GO:0001701 IEA in utero embryonic development
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0032715 IEA negative regulation of interleukin-6 production
GO:0034101 IEA erythrocyte homeostasis
GO:0034616 IEA response to laminar fluid shear stress
GO:0035264 IEA multicellular organism growth
GO:0036003 IMP positive regulation of transcription from RNA polymerase II promoter in response to stress
GO:0040029 IEA regulation of gene expression, epigenetic
GO:0043249 IEA erythrocyte maturation
GO:0043565 IEA sequence-specific DNA binding
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0051247 IGI positive regulation of protein metabolic process
GO:0060509 IEA Type I pneumocyte differentiation
GO:0070301 IEA cellular response to hydrogen peroxide
GO:0071347 IEA cellular response to interleukin-1
GO:0071356 IEA cellular response to tumor necrosis factor
GO:0071407 IEA cellular response to organic cyclic compound
GO:0071409 IEA cellular response to cycloheximide
GO:0071499 IMP cellular response to laminar fluid shear stress
GO:1901653 IEA cellular response to peptide

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040432 klf2b Kruppel-like factor 2b protein_coding Danio_rerio
ENSDARG00000042667 klf2a Kruppel-like factor 2a protein_coding Danio_rerio
ENSMUSG00000055148 Klf2 Kruppel-like factor 2 (lung) protein_coding Mus_musculus

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